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  1. No Access

    Article

    Role of m6A modifications in immune evasion and immunotherapy

    RNA modification has garnered increasing attention in recent years due to its pivotal role in tumorigenesis and immune surveillance. N6-methyladenosine (m6A) modification is the most prevalent RNA modification, w...

    Chunyu Wu, Lvyuan Li, Qiling Tang, Qian** Liao, Pan Chen, Can Guo… in Medical Oncology (2024)

  2. No Access

    Article

    Efficacy and Safety of Different Doses of Rivaroxaban and Risk Factors for Bleeding in Elderly Patients with Venous Thromboembolism: A Real-World, Multicenter, Observational, Cohort Study

    Venous thromboembolism (VTE) consists of deep vein thrombosis (DVT) and pulmonary embolism (PE). Rivaroxaban is a direct oral anticoagulant (DOAC) inhibiting activated coagulation factor X (FXa), and exerts se...

    Kepeng Lu, Qian-Qian Liao, Ke-Wei Zhu, Ying Yao, **ao-Jiao Cui… in Advances in Therapy (2024)

  3. Article

    Open Access

    Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

    This prospective multicenter phase II study evaluated the clinical efficacy of neoadjuvant nivolumab-exclusive (N) and nivolumab–chemotherapy (N/C) combinations based on PD-L1 expression. Eligible patients exh...

    Si-Yang Liu, Song Dong, Xue-Ning Yang… in Signal Transduction and Targeted Therapy (2023)

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  4. Article

    Open Access

    Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

    EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell l...

    Wen-Zhao Zhong, Hong-Hong Yan, Ke-Neng Chen… in Signal Transduction and Targeted Therapy (2023)

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  5. Article

    Open Access

    SRC-3/TRAF4 facilitates ovarian cancer development by activating the PI3K/AKT signaling pathway

    Ovarian cancer is the seventh most common cancer in women, and it causes many deaths in women worldwide. Patients with ovarian cancer have a poor prognosis and low survival rate. This study aimed to explore th...

    Ying Wang, **a Luo, Nayiyuan Wu, Qian** Liao, **g Wang in Medical Oncology (2023)

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  6. Article

    Open Access

    The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity

    Cancer metabolic reprogramming enhances its malignant behaviors and drug resistance, which is regulated by POU domain transcription factors. This study explored the effect of POU domain class 2 transcription f...

    **guan Lin, Longzheng **a, Linda Oyang, Jiaxin Liang, Shiming Tan, Nayiyuan Wu… in Oncogene (2022)

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  7. No Access

    Article

    BPIFB1 inhibits vasculogenic mimicry via downregulation of GLUT1-mediated H3K27 acetylation in nasopharyngeal carcinoma

    Nasopharyngeal carcinoma (NPC) demonstrates significant regional differences and a high incidence in Southeast Asia and Southern China. Bactericidal/permeability-increasing-fold- containing family B member 1 (...

    **anjie Jiang, **angying Deng, Jie Wang, Yongzhen Mo, Lei Shi, Fang Wei… in Oncogene (2022)

  8. Article

    Open Access

    Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc

    Actin filament associated protein 1 antisense RNA 1 (named AFAP1-AS1) is a long non-coding RNA and overexpressed in many cancers. This study aimed to identify the role and mechanism of AFAP1-AS1 in lung cancer...

    Yu Zhong, Liting Yang, Fang **ong, Yi He… in Signal Transduction and Targeted Therapy (2021)

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  9. No Access

    Article

    circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma

    Circular RNAs (circRNAs) play an essential role in tumorigenesis and development. However, they have rarely been investigated in nasopharyngeal carcinoma (NPC). This study aimed to investigate the role of circ...

    Le Tang, Wei **ong, Lishen Zhang, Dan Wang, Yian Wang, Yingfen Wu, Fang Wei… in Oncogene (2021)

  10. Article

    Open Access

    LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma

    Long-palate, lung and nasal epithelium clone 1 (LPLUNC1) is a tumour suppressor gene in nasopharyngeal carcinoma (NPC), and low expression of LPLUNC1 is associated with poor prognosis. Our previous study showe...

    Heran Wang, Yujuan Zhou, Linda Oyang, Yaqian Han, Longzheng **a, **gguan Lin… in Oncogene (2019)

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  11. No Access

    Article

    Prognostic value of Twist and E-cadherin in patients with osteosarcoma

    Twist, a basic helix-loop-helix transcription factor, and E-cadherin are both correlated with the metastatic progression of several types of cancer. However, it is currently unknown whether their activations h...

    Ke Yin, Qiande Liao, Hongbo He, Da Zhong in Medical Oncology (2012)

  12. No Access

    Article

    The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma

    Dysregulation of microRNA (miRNA) metabolism has been observed in a variety of human cancers, but the expression patterns of the enzymes responsible for generating miRNAs remain largely unexplored. In this stu...

    **aofang Guo, Qian** Liao, Pan Chen… in Journal of Cancer Research and Clinical On… (2012)

  13. No Access

    Article

    Analysis of the contribution of nasopharyngeal epithelial cancer cells to the induction of a local inflammatory response

    We investigated the local contribution of nasopharyngeal epithelial cancer cells to the inflammatory process.

    Qian** Liao, **aofang Guo, **aoling Li… in Journal of Cancer Research and Clinical On… (2012)