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  1. Article

    Open Access

    Prevalence of pathogenic germline variants in the circulating tumor DNA testing

    Somatic and germline variants are not distinguishable by circulating tumor DNA (ctDNA) testing without analyzing non-tumor samples. Although confirmatory germline testing is clinically relevant, the criteria f...

    Yoshihiro Yamamoto, Keita Fukuyama… in International Journal of Clinical Oncology (2022)

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    Article

    Germline sequencing for presumed germline pathogenic variants via tumor-only comprehensive genomic profiling

    The European Society for Medical Oncology Precision Medicine Working Group (ESMO-PMWG) published recommendations regarding confirmatory germline testing for presumed germline pathogenic variants (PGPVs) in tum...

    Tomohiro Kondo, Yoshihiro Yamamoto… in International Journal of Clinical Oncology (2022)