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Article
Translation Initiation Factor eIF3 Probably Binds with Microtubules in Mammalian Cells
Association of the translation apparatus with the cytoskeleton is essential for its transportation within the cell and probably also for translation regulation. Very little is known about the involvement of pa...
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Article
Internal Ribosome Entry Site from Crucifer Tobamovirus Promotes Initiation of Translation in Escherichia coli
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Article
Reciprocal Dependence between Pectinmethylesterase Gene Expression and Tobamovirus Reproduction Effectiveness in Nicotiana benthamiana
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Article
Nuclear Localization Signals in p170, the Large Subunit of Translation Initiation Factor 3
Apart from their role in translation, eukaryotic translation factors or their individual subunits may perform other functions, in particular, regulating nuclear processes. Primary structure analysis revealed f...
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Article
Stress granules: RNP-containing cytoplasmic bodies arising in stress: Structure and mechanism of organization
The review considers recent data on stress granules, which are dense RNP-containing cytoplasmic bodies that arise under stress conditions, e.g., in heat shock, UV irradiation, energy depletion, and oxidative s...
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Article
Production of biologically active human myelocytokines in plants
An effective system for expression of human granulocyte and granulocyte macrophage colony-stimulating factors (hG-CSF and hGM-CSF) in Nicotiana benthamiana plants was developed using viral vector based on tobacco...
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Article
Cellular acidosis inhibits assembly, disassembly, and motility of stress granules
Stress granules (SGs) are large ribonucleoprotein (RNP)-containing particles that form in cytoplasm in response to a variety of acute changes in the cellular environment. One of the general parameters of the c...
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Article
Distribution of translation initiation factor eIF3 in neutrophils in Alzheimer disease
The distribution of initiation factor eIF3 in the cytoplasm of peripheral blood neutrophils in Alzheimer disease (AD) was investigated. Using a specially developed image analysis protocol, we found a significa...
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Article
Stimulation of Violacein Biosynthesis in Chromobacterium violaceum Biofilms in the Presence of Dimethyl Sulfoxide
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Article
Three Mutations in the Stalk Region of Hemagglutinin Affect the pH of Fusion and Pathogenicity of H5N1 Influenza Virus
Previously, an attenuated variant Ku/at was obtained from the highly pathogenic avian influenza virus A/chicken/Kurgan/3/2005 (H5N1) by a reverse selection method aimed at increasing the virus resistance to a ...
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Article
Complexes Formed via Bioconjugation of Genetically Modified TMV Particles with Conserved Influenza Antigen: Synthesis and Characterization
Recently we obtained complexes between genetically modified Tobacco Mosaic Virus (TMV) particles and proteins carrying conserved influenza antigen such as M2e epitope. Viral vector TMV-N-lys based on TMV-U1 genom...
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Article
The Effect of I155T, K156Q, K156E and N186K Mutations in Hemagglutinin on the Virulence and Reproduction of Influenza A/H5N1 Viruses
The continued circulation of influenza A virus subtype H5 may cause the emergence of new potential pandemic virus variants, which can be transmitted from person to person. The occurrence of such variants is ma...
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Article
Latex Agglutination as an Alternative to the Hemagglutination Reaction of Influenza Viruses
Abstract—As an alternative to the classical method of erythrocyte hemagglutination, a latex agglutination assay based on the interaction of influenza viruses with the sialoglycoprotein fetuin immobilized on the s...