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    Article

    A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development

    Epithelial-to-mesenchymal transition (EMT) renders epithelial cells migratory properties. While epigenetic and splicing changes have been implicated in EMT, the mechanisms governing their crosstalk remain poor...

    Sanjeeb Kumar Sahu, Eneritz Agirre, Mohammed Inayatullah… in Nature Cell Biology (2022)

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    Open Access

    Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression

    Conditional gene activation is an efficient strategy for studying gene function in genetically modified animals. Among the presently available gene switches, the tetracycline-regulated system has attracted con...

    Simone Wörtge, Leonid Eshkind, Nina Cabezas-Wallscheid… in BMC Developmental Biology (2010)

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