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Article

Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression

Conditional gene activation is an efficient strategy for studying gene function in genetically modified animals. Among the presently available gene switches, the tetracycline-regulated system has attracted con...

Simone Wörtge, Leonid Eshkind, Nina Cabezas-Wallscheid… in BMC Developmental Biology (2010)