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    Article

    RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer

    RUNX3 is frequently inactivated by DNA hypermethylation in numerous cancers. Here, we show that RUNX3 has an important role in modulating apoptosis in immediate response to tumor necrosis factor-related apopto...

    Bo Ram Kim, Seong Hye Park, Yoon A Jeong, Yoo ** Na, Jung Lim Kim, Min Jee Jo… in Oncogene (2019)

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    Article

    Activating CCT2 triggers Gli-1 activation during hypoxic condition in colorectal cancer

    Hypoxia, or the deficiency of oxygen, in solid tumors is majorly responsible for the progression of cancer and remains unaffected by chemotherapy, but still requires definitive definition of the hypoxia signal...

    Seong Hye Park, Soyeon Jeong, Bo Ram Kim, Yoon A Jeong, Jung Lim Kim… in Oncogene (2020)