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  1. No Access

    Article

    Difference in formation mechanism of inclusion complex between configuration isomers of gallate-type catechin and β-cyclodextrin

    The formation mechanism of inclusion complex between (-)-epigallocatechin gallate (EGCg), which is the main catechin in tea leaves, or (-)-gallocatechin gallate (GCg), which is an isomer of EGCg, and β-cyclode...

    Hirohito Ikeda, Tomonori Ohata, Miho Yukawa… in Journal of Thermal Analysis and Calorimetry (2019)

  2. No Access

    Article

    Effect of solution pH on complex formation between epi-type catechin and β-cyclodextrin

    The effect of solution pH on the formation of an inclusion complex between (−)-epigallocatechin gallate (EGCg: pKa = 7.5) and β-cyclodextrin (β-CD) was investigated by isothermal titration calorimetry and 1H-NMR ...

    Tomonori Ohata, Hirohito Ikeda… in Journal of Thermal Analysis and Calorimetry (2019)

  3. No Access

    Article

    Improving water solubility of nateglinide by complexation of β-cyclodextrin

    Inclusion complex of anionic nateglinide (NTG) with β-cyclodextrin (βCD) has been prepared to improve the water solubility of NTG. The mechanism of the complexation was elucidated using isothermal titration ca...

    Hirohito Ikeda, Yuri Fukushige… in Journal of Thermal Analysis and Calorimetry (2016)

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    Article

    Drug–tea polyphenol interaction

    Propericiazine (PCZ) is an antipsychotic agent used for the treatment and the prevention of relapse of schizophrenia. We found that when an oral solution containing PCZ was mixed with a green tea drink, the re...

    Hirohito Ikeda, Yukiko Sano… in Journal of Thermal Analysis and Calorimetry (2013)