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    Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior

    The persistence of negative affect in pain leads to co-morbid symptoms such as anhedonia and depression—major health issues in the United States. The neuronal circuitry and contribution of specific cellular po...

    Tamara Markovic, Christian E. Pedersen, Nicolas Massaly in Nature Neuroscience (2021)

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    Author Correction: Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement

    Ream Al-Hasani, Raajaram Gowrishankar, Gavin P. Schmitz in Nature Neuroscience (2021)

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    Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement

    The long-range GABAergic input from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) is relatively understudied, and therefore its role in reward processing has remained unknown. In the present ...

    Ream Al-Hasani, Raajaram Gowrishankar, Gavin P. Schmitz in Nature Neuroscience (2021)

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    Wireless optofluidic brain probes for chronic neuropharmacology and photostimulation

    Both in vivo neuropharmacology and optogenetic stimulation can be used to decode neural circuitry, and can provide therapeutic strategies for brain disorders. However, current neuronal interfaces hinder long-t...

    Raza Qazi, Adrian M. Gomez, Daniel C. Castro, Zhanan Zou in Nature Biomedical Engineering (2019)

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    Polymorphic computation in locus coeruleus networks

    Physiological and optogenetic dissection of discrete locus coeruleus neuronal populations reveals a functional disassociation, with heterogeneous engagement of locus coeruleus neurons in either fear learning o...

    Dong-oh Seo, Michael R Bruchas in Nature Neuroscience (2017)

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    Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

    Optogenetic studies of the peripheral nervous system and spinal cord are enabled by soft, wirelessly powered biocompatible devices.

    Sung Il Park, Daniel S Brenner, Gunchul Shin, Clinton D Morgan in Nature Biotechnology (2015)