5 Result(s)
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Article
Michael E. Murphy
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Article
Open AccessA multicentre evaluation and expert recommendations of use of the newly developed BioFire Joint Infection polymerase chain reaction panel
Septic arthritis is a serious condition with significant morbidity and mortality, routinely diagnosed using culture. The FDA has recently approved the rapid molecular BioFire® Joint Infection Panel (BJIP) for ...
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Open AccessToxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status
The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure...
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Open AccessToxicity associated with tuberculosis chemotherapy in the REMoxTB study
The incidence and severity of tuberculosis chemotherapy toxicity is poorly characterised. We used data available from patients in the REMoxTB trial to provide an assessment of the risks associated with the sta...
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Open AccessLiver toxicity associated with tuberculosis chemotherapy in the REMoxTB study
Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of predisposing factors and the natural history i...
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Open AccessSpot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis
The use of early morning sputum samples (EMS) to diagnose tuberculosis (TB) can result in treatment delay given the need for the patient to return to the clinic with the EMS, increasing the chance of patients ...
