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Article
Preventive effects of Ramelteon on bleomycin-induced pulmonary fibrosis in mice
Pulmonary fibrosis (PF) is a devastating lung disease that leads to impaired lung function and ultimately death. Several studies have suggested that melatonin, a hormone involved in regulating sleep–wake cycle...
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Article
Predefined Performance Fuzzy Control for Hysteresis Stochastic Nonlinear Systems
Predefined performance control (PPC) has been applied to many engineering fields, such as unmanned aerial vehicle, emergency braking, and so on. Note that above engineering applications have the characteristic...
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Article
Open AccessLysSYL: a broad-spectrum phage endolysin targeting Staphylococcus species and eradicating S. aureus biofilms
Staphylococcus aureus and its single or mixed biofilm infections seriously threaten global public health. Phage therapy, which uses active phage particles or phage-derived endolysins, has emerged as a promising a...
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Article
HPFG: semi-supervised medical image segmentation framework based on hybrid pseudo-label and feature-guiding
Semi-supervised learning methods have been attracting much attention in medical image segmentation due to the lack of high-quality annotation. To cope with the noise problem of pseudo-label in semi-supervised ...
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Article
Open AccessCircular RNA-circPan3 attenuates cardiac hypertrophy via miR-320-3p/HSP20 axis
Circular RNAs are enriched in cardiac tissue and play important roles in the pathogenesis of heart diseases. In this study, we aimed to investigate the regulatory mechanism of a conserved heart-enriched circRN...
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Article
Open AccessA hard molecular nanomagnet from confined paramagnetic 3d-4f spins inside a fullerene cage
Reducing inter-spin distance can enhance magnetic interactions and allow for the realization of outstanding magnetic properties. However, achieving reduced distances is technically challenging. Here, we constr...
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Article
Adapting Legal Education for the Changing Landscape of Regional Emerging Economies: A Dynamic Framework for Law Majors
Drawing from an exhaustive exploration of the evolving demand for legal professionals within the dynamic landscape of regional emerging economies, this paper meticulously examines the intricate interplay betwe...
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Article
Electrosynthesis of amino acids from NO and α-keto acids using two decoupled flow reactors
Amino acids have wide application in the food and pharmaceutical industries. Current biotic and chemical syntheses suffer from low efficiency, complex purification operations and high energy consumption. Here ...
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Article
Fixed Time Adaptive Fuzzy Dynamic Surface Control for Pure Feedback Stochastic Nonlinear Systems
In this paper, an adaptive fuzzy fixed time control strategy based on dynamic surface control (DSC) method is proposed for pure feedback stochastic nonlinear systems with external disturbances. The mean value ...
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Article
TPFR-Net: U-shaped model for lung nodule segmentation based on transformer pooling and dual-attention feature reorganization
Accurate segmentation of lung nodules is the key to diagnosing the lesion type of lung nodule. The complex boundaries of lung nodules and the visual similarity to surrounding tissues make precise segmentation ...
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Article
Electrosynthesis of 15N-labeled amino acids from 15N-nitrite and ketonic acids
15N isotope-labeled amino acids (15N-amino acids) are crucial in the fields of biology, medicine, and chemistry. 15N-amino acids are conventionally synthesized through microbial fermentation and chemical reductiv...
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Article
Open AccessTherapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria
Gram-positive (G+) bacterial infection is a great burden to both healthcare and community medical resources. As a result of the increasing prevalence of multidrug-resistant G+ bacteria such as methicillin-resista...
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Article
English-medium journals as a bridge: A study of Frontiers of Education in China
International scholarly relations have been hegemonic in form and Euro-American in content. In academic publishing, inequalities have been widely sustained. This case is even worse in the human and social scie...
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Article
Dynamical analysis of a kind of two-stage tumor-immune model under Gaussian white noises
In this paper, a two-stage tumor-immune system with Gaussian white noises is investigated in order to understand the interaction mechanism between tumor cells and the immune system. Based on Langevin theory an...
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Article
Investigating annotation noise for named entity recognition
Recent studies revealed that even the most widely used benchmark dataset still contains more than 5% sample-level annotation noise in Named Entity Recognition (NER). Hence, we investigate annotation noise in t...
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Article
Open AccessTadalafil increases the antitumor activity of 5-FU through inhibiting PRMT5-mediated glycolysis and cell proliferation in colorectal cancer
Protein arginine methyltransferase 5 (PRMT5) is upregulated in multiple tumors and plays a pivotal role in cancer cell proliferation. However, the role of PRMT5 in colorectal cancer remains poorly understood.
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Article
Triple discriminators - equipped GAN for Denoising of Chinese calligraphic tablet images
Denoising of Chinese calligraphic tablet images is of great importance in regard to the study of both content and character shapes in these images. Formerly GAN (generative adversarial network) based image den...
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Article
Open AccessElectrocatalytic hydrogenation of quinolines with water over a fluorine-modified cobalt catalyst
Room temperature and selective hydrogenation of quinolines to 1,2,3,4-tetrahydroquinolines using a safe and clean hydrogen donor catalyzed by cost-effective materials is significant yet challenging because of ...
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Article
Failure Analysis and Service Properties of 20Cr1Mo1VNbTiB Bolt in 660 MW Supercritical Thermal Power Unit
Failure cause and service properties of 20Cr1Mo1VNbTiB bolts in a 660 MW supercritical thermal power unit have been studied. The bolts fractured with evidence of material aging. Chemical analysis, microstructu...
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Article
Risk factors of persistent subretinal fluid after half-dose photodynamic therapy for treatment-naïve central serous chorioretinopathy
To investigate the prognostic factors on spectral domain optical coherence tomography (SD-OCT) associated with incomplete subretinal fluid (SRF) absorption in treated-naïve eyes with central serous chorioretin...