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    Article

    Experimental congenital diaphragmatic hernia features an alteration of DNA sensing targets cGAS and STING

    The pathogenesis of congenital diaphragmatic hernia (CDH) depends on multiple factors. Activation of the DNA-sensing cyclic-GMP-AMP-synthase (cGAS) and Stimulator-of-Interferon-Genes (STING) pathway by double-...

    Moritz Markel, Wai Hei Tse, Nolan De Leon, Marietta Jank in Pediatric Research (2024)

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    Article

    Prenatal maternal biomarkers for the early diagnosis of congenital malformations: A review

    Congenital anomalies cause ~7% of all neonatal deaths, many of which have no identified pathophysiological cause. Because accurate and robust laboratory tests are unavailable for most birth defects, physicians...

    Richard Wagner, Wai Hei Tse, Jan-Hendrik Gosemann, Martin Lacher in Pediatric Research (2019)

  3. Article

    The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice

    Necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disease in premature infants with high mortality and morbidity with uncertain pathogenesis. Recent research focused on the role of intralu...

    Marco Ginzel, Yi Yu, Christian Klemann, **aoyan Feng in Pediatric Research (2016)