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Article
Experimental congenital diaphragmatic hernia features an alteration of DNA sensing targets cGAS and STING
The pathogenesis of congenital diaphragmatic hernia (CDH) depends on multiple factors. Activation of the DNA-sensing cyclic-GMP-AMP-synthase (cGAS) and Stimulator-of-Interferon-Genes (STING) pathway by double-...
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Article
Prenatal maternal biomarkers for the early diagnosis of congenital malformations: A review
Congenital anomalies cause ~7% of all neonatal deaths, many of which have no identified pathophysiological cause. Because accurate and robust laboratory tests are unavailable for most birth defects, physicians...
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Article
The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice
Necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disease in premature infants with high mortality and morbidity with uncertain pathogenesis. Recent research focused on the role of intralu...