3 Result(s)
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Article
Lisa Prevedel
Science, Humanities and Social Sciences, multidisciplinary
Science, multidisciplinary
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Article
Open AccessHIV infection and latency induce a unique metabolic signature in human macrophages
Currently, a major barrier to curing HIV infection is the generation of tissue-associated, non-replicating, long-lasting viral reservoirs that are refractory to therapy and can be reactivated upon anti-retrovi...
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Article
Open AccessTunneling nanotubes (TNT) mediate long-range gap junctional communication: Implications for HIV cell to cell spread
Cell-to-cell communication is essen for the development of multicellular systems and is coordinated by soluble factors, exosomes, gap junction (GJ) channels, and the recently described tunneling nanotubes (TNT...
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Article
Open AccessHIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim
While HIV kills most of the cells it infects, a small number of infected cells survive and become latent viral reservoirs, posing a significant barrier to HIV eradication. However, the mechanism by which immun...
