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Article
Contrast CT radiomic features add value to prediction of prognosis in adrenal cortical carcinoma
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis due to high postoperative recurrence rates. The aim of this study is to develop a contrast CT radiomic feature-based progn...
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Article
Open AccessThe architecture of substrate-engaged TOM–TIM23 supercomplex reveals preprotein proximity sites for mitochondrial protein translocation
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Article
Open AccessMeckel’s diverticulum mimicking acute appendicitis in children: a retrospective cohort study
The aims of this study were to summarize the clinical presentation and histological results of 20 cases of complicated Meckel diverticulum (MD) who were presumed to have acute appendicitis before surgery, as w...
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Article
Open AccessConstruction and validation of a competency model for hospital operation assistant of public hospitals in China: a cross‑sectional study
Hospital operation assistant (HOA) plays an important role in promoting the operation effectiveness and efficiency of hospital. China, as a resource-poor country, urgently needs to train HOA talent. The purpos...
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Article
Mechanism of the Interaction Between Hydrogen, Microstructure, and Mechanical Properties in Low-Alloy High-Strength Marine Steel
Herein, the interaction between hydrogen, microstructure, and mechanical properties in low-alloy high-strength marine steel was elucidated via microstructural characterization, internal friction analysis, hydr...
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Article
Effective elimination of hexavalent chromium and lead from solution by the modified biochar with MgMn2O4 nanoparticles: adsorption performance and mechanism
Heavy metal pollution is one of the environmental problems that need to be solved urgently. The adsorption method is thought as the most effective and economical treatment technology. Nature biochar usually sh...
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Article
Open AccessCSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages
Microglia are known to regulate stress and anxiety in both humans and animal models. Psychosocial stress is the most common risk factor for the development of schizophrenia. However, how microglia/brain macrop...
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Article
A qualitative research exploring the experiences of patients receiving immune checkpoint inhibitors for advanced lung cancer
In patients with advanced lung cancer, immune checkpoint inhibitors (ICIs) dramatically extended survival. We aimed to investigate the experiences of patients with advanced lung cancer who are receiving ICIs, ...
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Article
Open AccessComparison of partial nephrectomy and radical nephrectomy for cystic renal cell carcinoma: a SEER-based and retrospective study
Cystic renal cell carcinoma (cRCC) is uncommon and surgical indication remains controversial. We compared radical nephrectomy (RN) with partial nephrectomy (PN) in patients with cRCC using data from the Survei...
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Article
Clinicopathologic and prognostic factors for colorectal cancer in children and adolescents: a population-based study
Colorectal cancer (CRC) is rarely found in children and adolescents. The purpose of this study was to retrospectively conduct a population-based cohort of pediatric patients with CRC.
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Article
Brain Activation Site of Laryngeal Elevation During Swallowing: An fMRI Study
The object of this study is to investigate dysphagia caused by reduced laryngeal elevation in patients poststroke. The central mechanism of laryngeal elevation during swallowing was explored by comparing the b...
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Article
Taurine Treatment Alleviates Intestinal Mucositis Induced by 5-Fluorouracil in Mice
Taurine (Tau), a β-amino acid, exists in red goji fruit (Lycium barbarum L.). It exerts many cellular physiological functions such as anti-inflammation and oxidation resistance. The chemotherapy drug 5-fluorourac...
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Article
Modified photoperiod response of CsFT promotes day neutrality and early flowering in cultivated cucumber
Map-based cloning and photoperiod response detection suggested that CsFT is the critical gene for cucumber photoperiod domestication.
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Article
Open AccessThe dynamic changes of HBV quasispecies diversity in infancy after immunoprophylaxis failure: a prospective cohort study
Previous works have observed that younger infants with chronic hepatitis B virus (HBV) infection are more responsive to antiviral treatment. However, the underlying mechanism remains unclear. In this study, th...
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Article
Open AccessRapid detection of avian leukosis virus subgroup J by cross-priming amplification
Avian leukosis virus subgroup J (ALV-J) causes oncogenic disease in chickens in China, resulting in great harm to poultry production, and remains widespread in China. Herein, we employed a cross-priming amplif...
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Article
Open AccessStructural insights into assembly of human mitochondrial translocase TOM complex
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Article
Open AccessPrognostic value of Glypican family genes in early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy and possible mechanisms
This study explored the prognostic significance of Glypican (GPC) family genes in patients with pancreatic ductal adenocarcinoma (PDAC) after pancreaticoduodenectomy using data from The Cancer Genome Atlas (TC...
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Article
The prognostic value of combined tumor markers and systemic immune-inflammation index in colorectal cancer patients
This study evaluated the significance of combining tumor markers (TM) and systemic immune-inflammation index (SII) for postoperative complications and long-term outcomes in colorectal cancer (CRC) patients.
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Article
Effect of large load on the wear and corrosion behavior of high-strength EH47 hull steel in 3.5wt% NaCl solution with sand
To simulate the wear and corrosion behavior of high-strength EH47 hull steel in a complicated marine environment in which seawater, sea ice, and sea sand coexist, accelerated wear and corrosion tests were perf...
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Article
Open AccessThe value of L3 skeletal muscle index in evaluating preoperative nutritional risk and long-term prognosis in colorectal cancer patients
L3 skeletal muscle index (L3SMI) was reportedly related to postoperative outcomes. We aimed to investigate the value of L3SMI in evaluating preoperative nutritional risk and long-term prognosis in colorectal c...