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  1. Article

    Open Access

    CRLF1 promotes malignant phenotypes of papillary thyroid carcinoma by activating the MAPK/ERK and PI3K/AKT pathways

    Papillary thyroid carcinoma (PTC) is the one of the most common types of endocrine cancer and has a heterogeneous prognosis. Tumors from patients with poor prognosis may differentially express specific genes. ...

    Shi-Tong Yu, Qian Zhong, Ren-Hui Chen, ** Han, Shi-Bing Li in Cell Death & Disease (2018)

  2. Article

    Open Access

    RETRACTED ARTICLE: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p

    Dysregulation of RKIP and NRF2 has been widely involved in the therapy resistance of multiple malignances, however, their relation and the corresponding mechanisms, especially in radiation response, have not b...

    Wei Huang, Guangqing Shi, Zhong Yong, Jian Li, Juan Qiu, Yan Cao in Cell Death & Disease (2020)

  3. Article

    Open Access

    SIRT1 attenuates renal fibrosis by repressing HIF-2α

    Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulatio...

    Peipei Li, Yue Liu, **aogang Qin, Kairen Chen, Ruiting Wang in Cell Death Discovery (2021)

  4. Article

    Open Access

    Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis

    Circular RNAs (circRNAs) are known to act as key regulators in a variety of malignancies. However, the role of circRNAs in cervical cancer (CCa) remains largely unknown. Herein, we demonstrated that a circRNA ...

    Chunyu Zhang, Pan Liu, Jiaming Huang, Yuandong Liao, Chaoyun Pan in Cell Death & Disease (2021)

  5. No Access

    Article

    LINC00313 facilitates osteosarcoma carcinogenesis and metastasis through enhancing EZH2 mRNA stability and EZH2-mediated silence of PTEN expression

    Osteosarcoma is one of the five leading causes of cancer death among all pediatric malignancies. Recent advances in non-coding RNAs suggested that many long noncoding RNAs (lncRNAs) are dysregulated in cancer ...

    Chun-Yang **ng, Yu-Zhu Zhang, Wei Hu, Li-Yuan Zhao in Cellular and Molecular Life Sciences (2022)

  6. Article

    Open Access

    EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

    Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC). However, its ass...

    Li Yuan, Shibing Li, Qiuyan Chen, Tianliang **a in Cell Death & Differentiation (2022)

  7. Article

    Open Access

    Retraction Note: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/ NQO1 axis via downregulating miR-450b-5p

    Wei Huang, Guangqing Shi, Zhong Yong, Jian Li, Juan Qiu, Yan Cao in Cell Death & Disease (2023)