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  1. Article

    Open Access

    Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families

    In family-based association analysis, each family is typically ascertained from a single proband, which renders the effects of ascertainment bias heterogeneous among family members. This is contrary to case–co...

    Suyeon Park, Sungyoung Lee, Young Lee, Christine Herold in BMC Medical Genetics (2015)

  2. No Access

    Article

    Assessment of Alzheimer’s disease case–control associations using family-based methods

    The genetics of Alzheimer’s disease (AD) is heterogeneous and remains only ill-defined. We have recently created a freely available and continuously updated online database (AlzGene; http://www...

    Brit-Maren M. Schjeide, Matthew B. McQueen, Kristina Mullin, Jason DiVito in neurogenetics (2009)

  3. No Access

    Article

    Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

    The past decade has witnessed hundreds of reports declaring or refuting genetic association with putative Alzheimer disease susceptibility genes. This wealth of information has become increasingly difficult to...

    Lars Bertram, Matthew B McQueen, Kristina Mullin, Deborah Blacker in Nature Genetics (2007)