18 Result(s)
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Article
Kazunori Sasaki
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Open AccessPrimordial aqueous alteration recorded in water-soluble organic molecules from the carbonaceous asteroid (162173) Ryugu
We report primordial aqueous alteration signatures in water-soluble organic molecules from the carbonaceous asteroid (162173) Ryugu by the Hayabusa2 spacecraft of JAXA. Newly identified low-molecular-weight hy...
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GC-MS-Guided Antimicrobial Defense Responsive Secondary Metabolites from the Endophytic Fusarium solani Isolated from Tinospora cordifolia and Their Multifaceted Biological Properties
Medicinal plants are hosts to an infinite number of microorganisms, commonly referred to as endophytes which are rich in bioactive metabolites yielding favorable biological activities. The endophytes are known...
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Identification and characterization of Fusarium commune, a causal agent of lotus rhizome rot
Lotus rhizome rot is one of the most important diseases affecting lotus production, leading to heavy economic losses in Japan. In this study, a causal agent of lotus rhizome rot in Yamaguchi prefecture, Japan,...
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Significance of Bryophyllum pinnatum (Lam.) for green synthesis of anti-bacterial copper and selenium nanoparticles and their influence on soil microflora
Green copper nanoparticles (CuNPs) and selenium nanoparticles (SeNPs) are synthesised by combining the leaf extract of Bryophyllum pinnatum with 25 mM of copper sulphate (CuSO4) and sodium selenite (Na2SeO3), res...
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Open AccessUracil in the carbonaceous asteroid (162173) Ryugu
The pristine sample from the near-Earth carbonaceous asteroid (162173) Ryugu collected by the Hayabusa2 spacecraft enabled us to analyze the pristine extraterrestrial material without uncontrolled exposure to ...
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Genotypic characterization of Plasmodiophora brassicae in the paddy-field weed Cardamine occulta and symptomology reveal a distinct pathogen population in Japan
Cruciferous clubroot, caused by the obligate protist Plasmodiophora brassicae, is one of the most destructive diseases of Brassicaceae crops worldwide. Clubroot is also frequently diagnosed in Cardamine occulta, ...
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Acyl-CoA dehydrogenase long chain (ACADL) is a target protein of stylissatin A, an anti-inflammatory cyclic heptapeptide
Stylissatin A (SA) is a cyclic heptapeptide isolated from the marine sponge Stylissa massa. SA shows anti-inflammatory activity against lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cells, but th...
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Open AccessThe role of Mediator and Little Elongation Complex in transcription termination
Mediator is a coregulatory complex that regulates transcription of Pol II-dependent genes. Previously, we showed that human Mediator subunit MED26 plays a role in the recruitment of Super Elongation Complex (S...
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CLEAN-NET: a modified laparoendoscopic wedge resection of the stomach to minimize the sacrifice of innocent gastric wall
To avoid excessive sacrifice of the tissue surrounding the submucosal tumor in gastric wedge resection with a stapling device, we perform a “combined laparoscopic and endoscopic approach for neoplasia with a n...
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Open AccessAnti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil
Mood disorder accounts for 13 % of global disease burden. And while therapeutic agents are available, usually orally administered, most have unwanted side effects, and thus making the inhalation of essential o...
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Metabolome analysis reveals the association between the kynurenine pathway and human herpesvirus 6 encephalopathy in immunocompetent children
Human herpesvirus 6 (HHV-6) is the second most common causative pathogen of acute encephalopathy in immunocompetent children in Japan. Identification of biomarkers associated the pathophysiology is desirable t...
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Neuroprotective effect of Picholine virgin olive oil and its hydroxycinnamic acids component against β-amyloid-induced toxicity in SH-SY5Y neurotypic cells
The health benefits of Mediterranean diet has long been reported and attributed to the consumption of virgin olive oil (VOO). Here, we evaluated the neuroprotective effect of VOO against Alzheimer’s disease by...
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Quantitative metabolome profiling reveals the involvement of the kynurenine pathway in influenza-associated encephalopathy
Influenza-associated encephalopathy is a serious complication of influenza and is the most common form of acute encephalitis/encephalopathy in Japan. The number of reports from other countries is increasing, r...
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Detection and quantification of onion isolates of Fusarium oxysporum f. sp. cepae in onion plant
Fusarium oxysporum f. sp. cepae (FOC) isolated from onion basal rot possessed a SIX3 homolog (FocSIX3) with 91.4 % identity to the SIX3 gene (FolSIX3) of F. oxysporum f. sp. lycopersici (FOL). A ...
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3,4,5-tri-O-caffeoylquinic acid inhibits amyloid β-mediated cellular toxicity on SH-SY5Y cells through the upregulation of PGAM1 and G3PDH
Caffeoylquinic acid (CQA) is one of the phenylpropanoids found in a variety of natural resources and foods, such as sweet potatoes, propolis, and coffee. Previously, we reported that 3,5-di-O-caffeoylquinic acid ...
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Selective proliferation of rat hepatocyte progenitor cells in serum-free culture
This protocol details a method of obtaining selectively proliferated hepatocyte progenitor cells using hyaluronic acid (HA)–coated dishes and serum-free medium. A small hepatocyte (SH) is a hepatocyte progenit...
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Malignant Melanoma of the Anorectum: Report of Four Cases
Four cases of anorectal malignant melanoma are reported in this paper. All patients underwent an abdominoperineal resection with lymph node dissection for a curative operation and received postoperative chemot...
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A model for antiHelicobacter pylori chemotherapy using an experimental murine infection withHelicobacter felis
Colonization ofHelicobacter felis was observed to continue for at least 24 weeks in a BALB/c mouse stomach after oral inoculation of the bacteria. Bacteria were observed on the surface of the gastric mucosa and i...
