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Article
Open AccessContributions of major smoking-related diseases to reduction in life expectancy associated with smoking in Chinese adults: a cross-sectional study
Cigarette smoking is a prominent risk factor for a wide range of diseases. The current study aimed to evaluate the impact of smoking on deaths from major smoking-related diseases (neoplasms, vascular diseases ...
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Article
Open AccessOverexpression of RBM5 induces autophagy in human lung adenocarcinoma cells
Dysfunctions in autophagy and apoptosis are closely interacted and play an important role in cancer development. RNA binding motif 5 (RBM5) is a tumor suppressor gene, which inhibits tumor cells’ growth and en...
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Article
Open AccessPassive smoking and stroke in men and women: a national population-based case-control study in China
An association between passive smoking and stroke is unclear in China, particularly the association with hemorrhagic stroke. This study included 16205 deaths due to stroke aged ≥30 years and 16205 non-stroke c...
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Article
Open AccessTRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has previously been demonstrated to play a pro-inflammatory role in allergic airways disease and COPD through the upregulation of the E3 ubiquit...
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Article
Open AccessIs exposure to tobacco associated with extrahepatic cholangiocarcinoma epidemics? A retrospective proportional mortality study in China
Extrahepatic cholangiocarcinoma (ECC) has become one of the most rapidly increasing malignancies in China during recent decades. The relationship between tobacco exposure and ECC epidemics is unclear; this stu...
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Article
Open AccessFactors controlling the spatial distribution of soil organic carbon in Daxing’anling Mountain
Daxing’anling Mountain, in the northeastern part of China, contains a large amount of soil organic carbon (SOC). Using data including topography, climate, and vegetation, the spatial distribution of SOC conten...
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Article
Open AccessThe mechanism of nicotinamide on reducing acute lung injury by inhibiting MAPK and NF-κB signal pathway
Acute lung injury is an important factor that leads to the death of patients with pneumonia. Previous studies have shown that nicotinamide (NAM) plays a role in reducing cell damage, so this study explored the...
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Article
A surface protein−imprinted biosensor based on boronate affinity for the detection of anti−human immunoglobulin G
A surface protein-imprinted biosensor was constructed on a screen-printed carbon electrode (SPCE) for the detection of anti-human immunoglobulin G (anti-IgG). The SPCE was successively decorated with aminated ...
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Article
Open AccessMenstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson’s disease models
Neuroinflammation is closely related to the development of Parkinson's disease (PD). Because of the extensive sources, non-invasive and periodical collection method, human menstrual blood-derived endometrial s...
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Article
Open AccessAssociations between ADHD and risk of six psychiatric disorders: a Mendelian randomization study
Observational studies and diagnostic criteria have indicated that Attention Deficit Hyperactivity Disorder (ADHD) frequently comorbid with various psychiatric disorders. Therefore, we conducted a Mendelian ran...
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Article
Open AccessThe effect of transcranial direct current stimulation (tDCS) on cognitive function recovery in patients with depression following electroconvulsive therapy (ECT): protocol for a randomized controlled trial
Electroconvulsive therapy (ECT) is a highly effective treatment for depressive disorder. However, the use of ECT is limited by its cognitive side effects (CSEs), and no specific intervention has been developed...
