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Serum is a rich source of ligands for the scavenger receptor of hepatic sinusoidal endothelial cells

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  1. Article

    Open Access

    Predictive value of p53, Ki67 and TLR5 in neoplastic progression of Barrett’s esophagus: a matched case–control study

    Barrett’s esophagus progresses to high-grade dysplasia or cancer along the well-established metaplasia-dysplasia-adenocarcinoma sequence. The aim of this study was to evaluate the value of p53, Ki67, and toll-...

    Olli Helminen, Jukka Melkko, Juha Saarnio, Eero Sihvo, Teijo Kuopio in Virchows Archiv (2022)

  2. Article

    Open Access

    Rheumatoid arthritis antigens homocitrulline and citrulline are generated by local myeloperoxidase and peptidyl arginine deiminases 2, 3 and 4 in rheumatoid nodule and synovial tissue

    Seropositive rheumatoid arthritis (RA) is characterized by autoantibodies binding to citrullinated and homocitrullinated proteins. We wanted to study the expression patterns of these disease-associated protein...

    Sanna Turunen, Johanna Huhtakangas, Tomi Nousiainen in Arthritis Research & Therapy (2016)

  3. Article

    Open Access

    Different amounts of protein-bound citrulline and homocitrulline in foot joint tissues of a patient with anti-citrullinated protein antibody positive erosive rheumatoid arthritis

    Antibodies binding to citrullinated proteins are a frequent finding in rheumatoid arthritis patients and may precede the onset of clinical symptoms several years. The antibodies are a predisposing factor for b...

    Sanna Turunen, Marja-Kaisa Koivula, Jukka Melkko in Journal of Translational Medicine (2013)