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  1. Article

    Open Access

    Fatigue, depression, and product tolerability during long-term treatment with intravenous immunoglobulin (Gamunex® 10%) in patients with chronic inflammatory demyelinating polyneuropathy

    Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is characterized by progressive weakness and sensory loss, often affecting patient’s ability to walk and perform activities of daily living inde...

    Juliane Klehmet, Björn Tackenberg, Judith Haas, Bernd C. Kieseier in BMC Neurology (2023)

  2. Article

    Open Access

    Long-term real-world effectiveness and safety of fingolimod over 5 years in Germany

    To evaluate the 5-year real-world benefit–risk profile of fingolimod in patients with relapsing–remitting MS (RRMS) in Germany.

    Tjalf Ziemssen, Michael Lang, Stephan Schmidt, Holger Albrecht in Journal of Neurology (2022)

  3. Article

    Open Access

    Therapy Switches in Fingolimod-Treated Patients with Multiple Sclerosis: Long-Term Experience from the German MS Registry

    Therapy switches in patients with multiple sclerosis (MS) receiving treatment with fingolimod occur frequently in clinical practice but are not well represented in real-world data. The aim of this study was to...

    Niklas Frahm, Firas Fneish, David Ellenberger, Peter Flachenecker in Neurology and Therapy (2022)

  4. Article

    Open Access

    Clinical and Demographic Profile of Patients Receiving Fingolimod in Clinical Practice in Germany and the Benefit–Risk Profile of Fingolimod After 1 Year of Treatment: Initial Results From the Observational, Noninterventional Study PANGAEA

    The population with multiple sclerosis receiving treatment in clinical practice differs from that in randomized controlled trials (RCTs). An assessment of the real-world benefit–risk profile of therapies is ne...

    Tjalf Ziemssen, Michael Lang, Björn Tackenberg, Stephan Schmidt in Neurotherapeutics (2018)

  5. Article

    Open Access

    Electrocardiographic assessments and cardiac events after fingolimod first dose – a comprehensive monitoring study

    First dose observation for cardiac effects is required for fingolimod, but recommendations on the extent vary. This study aims to assess cardiac safety of fingolimod first dose. Individual bradyarrhythmic epis...

    Volker Limmroth, Tjalf Ziemssen, Michael Lang, Stephan Richter in BMC Neurology (2017)

  6. Article

    Open Access

    Design of TRUST, a non-interventional, multicenter, 3-year prospective study investigating an integrated patient management approach in patients with relapsing-remitting multiple sclerosis treated with natalizumab

    Natalizumab provides rapid and high-efficacy control of multiple sclerosis disease activity with long-term stabilization. However, the benefits of the drug are countered by a risk of develo** progressive mul...

    Tjalf Ziemssen, Achim Gass, Jens Wuerfel, Antonios Bayas, Björn Tackenberg in BMC Neurology (2016)

  7. No Access

    Article

    Symptomatology of MS: results from the German MS Registry

    Since 2002, an MS Registry has been implemented by the German MS Society in more than 100 German MS centres. The objective is to provide information about disease characteristics, and to monitor the health car...

    Kristin Stuke, Peter Flachenecker, Uwe K. Zettl, Wolfgang G. Elias in Journal of Neurology (2009)

  8. No Access

    Article

    Current issues in immunomodulatory treatment of multiple sclerosis

    Dr. Martin Stangel, Ralf Gold, Achim Gass, Judith Haas, Stefan Jung in Journal of Neurology (2006)

  9. No Access

    Article

    Mycophenolate-mofetil in the treatment of refractory multiple sclerosis

    Norbert Ahrens, Abdulgabar Salama, Judith Haas in Journal of Neurology (2001)