10 Result(s)
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Article
Joseph Brown
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Article
Open AccessSamplot: a platform for structural variant visual validation and automated filtering
Visual validation is an important step to minimize false-positive predictions from structural variant (SV) detection. We present Samplot, a tool for creating images that display the read depth and sequence ali...
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Open AccessGo Get Data (GGD) is a framework that facilitates reproducible access to genomic data
The rapid increase in the amount of genomic data provides researchers with an opportunity to integrate diverse datasets and annotations when addressing a wide range of biological questions. However, genomic da...
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Open AccessATLAS: a Snakemake workflow for assembly, annotation, and genomic binning of metagenome sequence data
Metagenomics studies provide valuable insight into the composition and function of microbial populations from diverse environments; however, the data processing pipelines that rely on map** reads to gene cat...
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Open AccessGenomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis
Clostridium perfringens is a key pathogen in poultry-associated necrotic enteritis (NE). To date there are limited Whole Genome Sequencing based studies describing broiler-associated C. perfringens in healthy and...
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Open AccessBioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration
The Bioinformatics Resource Manager (BRM) is a web-based tool developed to facilitate identifier conversion and data integration for Homo sapiens (human), Mus musculus (mouse), Rattus norvegicus (rat), Danio reri...
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Open AccessSpatial distribution of prokaryotic communities in hypersaline soils
Increasing salinization in wetland systems is a major threat to ecosystem services carried out by microbial communities. Thus, it is paramount to understand how salinity drives both microbial community structu...
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Open AccessAuthor Correction: Improved genome recovery and integrated cell-size analyses of individual uncultured microbial cells and viral particles
The original version of this Article contained errors in the units of concentration of three reagents listed in the Methods. These errors have all been corrected in both the PDF and HTML versions of the Article.
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Open AccessImproved genome recovery and integrated cell-size analyses of individual uncultured microbial cells and viral particles
Microbial single-cell genomics can be used to provide insights into the metabolic potential, interactions, and evolution of uncultured microorganisms. Here we present WGA-X, a method based on multiple displace...
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HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer
miRNAs regulate the expression of genes in both normal physiology and disease. While miRNAs have been demonstrated to play a pivotal role in aspects of cancer biology, these reports have generally focused on t...
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Reduction in clinical assessment time using computer algorithms
A new mathematical procedure (BIDALGO) is suggested for application to the psychological testing field. BIDALGO, similar to past adaptive testing methods, is compared both with MMPI short-form efforts and appl...
