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Open AccessSerological evaluation of risk factors for exposure to malaria in a pre-elimination setting in Malaysian Borneo
Malaysia has reported no indigenous cases of P. falciparum and P. vivax for over 3 years. When transmission reaches such low levels, it is important to understand the individuals and locations where exposure risk...
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Open AccessEthical and practical considerations related to data sharing when collecting patient-reported outcomes in care-based child health research
The collection and use of patient reported outcomes (PROs) in care-based child health research raises challenging ethical and logistical questions. This paper offers an analysis of two questions related to PRO...
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Open AccessGenetic diversity of Plasmodium vivax reticulocyte binding protein 2b in global parasite populations
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) plays a critical role in parasite invasion of reticulocytes by binding the transferrin receptor 1. PvRBP2b is a vaccine candidate based on the negative c...
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Open AccessUsing working memory performance to predict mathematics performance 2 years on
A number of previous studies have used working memory components to predict mathematical performance in a variety of ways; however, there is no consideration of the contributions of the subcomponents of visuos...
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Open AccessLow fundamental and formant frequencies predict fighting ability among male mixed martial arts fighters
Human voice pitch is highly sexually dimorphic and eminently quantifiable, making it an ideal phenotype for studying the influence of sexual selection. In both traditional and industrial populations, lower pit...
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Empirical evidence for resilience of tropical forest photosynthesis in a warmer world
Tropical forests may be vulnerable to climate change1–3 if photosynthetic carbon uptake currently operates near a high temperature limit4–6. Predicting tropical forest function requires understanding the relative...
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Open AccessHighly sampled measurements in a controlled atmosphere at the Biosphere 2 Landscape Evolution Observatory
Land-atmosphere interactions at different temporal and spatial scales are important for our understanding of the Earth system and its modeling. The Landscape Evolution Observatory (LEO) at Biosphere 2, managed...
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Open AccessThe Relationship between Visuospatial Working Memory and Mathematical Performance in School-Aged Children: a Systematic Review
The body of research surrounding the relationship between visuospatial working memory (VSWM) and mathematics performance remains in its infancy. However, it is an area generating increasing interest as the per...
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Decreased basal hepatic glucose uptake in impaired fasting glucose
This research aimed to define the pathophysiological defects responsible for the elevated fasting plasma glucose (FPG) concentration and excessive rise in post-load plasma glucose observed in individuals with ...
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Open AccessThe frequency of tetracycline resistance genes co-detected with respiratory pathogens: a database mining study uncovering descriptive trends throughout the United States
The Center for Disease Control and Prevention (CDC) indicates that one of the largest problems threatening healthcare includes antibiotic resistance. Tetracycline, an effective antibiotic that has been in use ...
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1.8 Initial Triple Combination Therapy is Superior to Stepwise Add-On Conventional Therapy in Newly Diagnosed T2DM (72-OR)
Background: In UKPDS stepwise addition of metformin, sulfonylurea, and basal insulin reduced microvascular complications, but A1c rose progressively to > 8.5% and ~ 65% of individuals required insulin therapy ...
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The effect of lengthening Life Expectancy on future pension and Long-Term Care expenditure in England, 2007 to 2032
Background
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Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation
Recent studies reveal that young carriers of the fragile X premutation are at increased risk for psychiatric conditions, memory problems and executive deficits. Post mortem and structural MRI studies suggest t...
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Article
Newborn screening in North America
Newborn screening in North America dates to the early work of Bob Guthrie in the USA. Screening programmes in both the USA and Canada began in the early 1960s, with documented programmes in both countries as e...
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Seismic Hazards Assessment for Radioactive Waste Disposal Sites in Regions of Low Seismic Activity
A comparative tectonic quiescence and lack of earthquakes make the stable centres of continents attractive for siting long-term radioactive waste storage facilities. The low rates of deformation in such region...
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Open AccessQuality of care for hypertension in the United States
Despite heavy recent emphasis on blood pressure (BP) control, many patients fail to meet widely accepted goals. While access and adherence to therapy certainly play a role, another potential explanation is poo...
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Open AccessProfiling quality of care: Is there a role for peer review?
We sought to develop a more reliable structured implicit chart review instrument for use in assessing the quality of care for chronic disease and to examine if ratings are more reliable for conditions in which...
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Use of ambulance dispatch data as an early warning system for communitywide influenzalike illness, New York City
In 1998, the New York City Department of Health and the Mayor’s Office of Emergency Management began monitoring the volume of ambulance dispatch calls as a surveillance tool for biologic terrorism. We adapted ...
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Indinavir Pharmacokinetics during Different Phases of the Menstrual Cycle in HIV-Infected Women
Objective: To characterise the pharmacokinetics of indinavir during different phases of the menstrual cycle in HIV-infected women.
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Identifying Drug Rashes