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    Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions

    Comprehensive enhancer discovery is challenging because most enhancers, especially those contributing to complex diseases, have weak effects on gene expression. Our gene regulatory network modeling identified ...

    Renhe Luo, Jielin Yan, ** Woo Oh, Wang **, Dustin Shigaki, Wilfred Wong… in Nature Genetics (2023)