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  1. Article

    Erratum: Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study

    Correction to: Gene Therapy advance online publication, 19 May 2016; doi: 10.1038/gt.2016.41 The following statement should be noted under Conflict of Interest: 'KK, WH, and RK are named inventors on patents t...

    R Kaminski, R Bella, C Yin, J Otte, P Ferrante, H E Gendelman, H Li… in Gene Therapy (2016)

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    Article

    Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study

    A CRISPR/Cas9 gene editing strategy has been remarkable in excising segments of integrated HIV-1 DNA sequences from the genome of latently infected human cell lines and by introducing InDel mutations, suppress...

    R Kaminski, R Bella, C Yin, J Otte, P Ferrante, H E Gendelman, H Li… in Gene Therapy (2016)

  3. Article

    Eine Weight-of-Evidence-Studie zur Bewertung der Sedimentbelastung und des Fischrückgangs in der Oberen Donau

    Hintergrund und Ziel der Studie Die Fischbestände in der Donau sind seit Ende der 1980er-Jahre stark rückläufig. Trotz intensiver bestandsstützender Maßnahmen und einer verbesserten Wasserqualität entlang der Don...

    H. Hollert, K. Bluhm, S. Keiter, M. Böttcher… in Umweltwissenschaften und Schadstoff-Forsch… (2009)

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    Reaktivierung nach einer Herpes-simplex-Enzephalitis

    Im Falle einer Reaktivierung nach einer Herpes-simplex-Enzephalitis (HSE) ist eine klare Unterscheidung zwischen einer rekurrierenden Virusinfektion und einem Autoimmunprozess oft nicht möglich; beide pathophy...

    Dr. S. Vieker, A. Remmel-Spornhauer, W. Boksch… in Monatsschrift Kinderheilkunde (2007)

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    p27SJ, a novel protein in St John's Wort, that suppresses expression of HIV-1 genome

    Transcription of the HIV-1 genome is controlled by the cooperation of viral regulatory proteins and several host factors which bind to specific DNA sequences within the viral promoter spanning the long termina...

    N Darbinian-Sarkissian, A Darbinyan, J Otte, S Radhakrishnan, B E Sawaya… in Gene Therapy (2006)

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    Article

    Effect of different East Coast Fever control strategies on fertility, milk production and weight gain of Sanga cattle in the Central Province of Zambia

    Five different East Coast Fever (ECF) (Theileria parva infection) control strategies, based on tick control and/or ECF immunization, were tested in groups of traditionally managed Sanga cattle in the Central P...

    B. Minjauw, J. Otte, A.D. James, J.J. de Castro… in Experimental & Applied Acarology (1997)

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    Article

    Proteinase — Antiproteinase imbalance in meningitis: Determination of α 1 proteinase inhibitor (α 1PI), elastase — α-1PI complex, and elastase inhibition capacity in cerebrospinal fluid

    Mortality and long-term neurologic sequelae are still frequent complications of meningitis despite effective antibiotic treatment. This suggests that pathogen-independent inflammatory mechanisms may play an im...

    J. van Wees, F. -K. Tegtmeyer, J. Otte, W. G. Wood, J. Braun in Klinische Wochenschrift (1990)

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    Article

    Hyperthermia in cancer therapy

    Tumor hyperthermia is a rediscovered technique of oncotherapy which has confirmed value in many studies on cell cultures, rodent and mammalian tumors as well as first investigations on patients with tumors. Th...

    J. Otte in European Journal of Pediatrics (1988)

  9. Article

    ELASTASE-α1-PROTEINASE INHIBITOR IN NEONATAL SEPTICEMIA AND HYALINE MEMBRANE DISEASE

    Elastase, a neutral protease stored in the azurophillic granules of neutrophils, is immediately released during the process of phagocytosis and rapidly bound and inactivated by α1-proteinase inhibitor. This compl...

    Ch P Speer, M Gahr, J Otte, F Tetmeyer in Pediatric Research (1987)

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