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Article
Open AccessThe role of epigenetic modifications for the pathogenesis of Crohn's disease
Epigenetics has become a promising field for finding new biomarkers and improving diagnosis, prognosis, and drug response in inflammatory bowel disease. The number of people suffering from inflammatory bowel d...
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Article
Open AccessDetection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clam** and hybridisation probes
In the present study, we combined the PCR-clam** approach with melting curve analysis using mutant specific hybridisation probes and wild-type specific peptide nucleic acids (PNAs) to determine the genotypes...