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Article
Open AccessFecal calprotectin and platelet count predict histologic disease activity in pediatric ulcerative colitis: results from a projection-predictive feature selection
Especially for pediatric patients, proxies of mucosal inflammation are needed. The Pediatric Ulcerative Colitis Activity Index (PUCAI) has been established to predict clinical and endoscopic disease activity. ...
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Article
Open AccessHow can patient registries facilitate guideline-based healthcare? A retrospective analysis of the CEDATA-GPGE registry for pediatric inflammatory bowel disease
Early diagnosis is mandatory for the medical care of children and adolescents with pediatric-onset inflammatory bowel disease (PIBD). International guidelines (‘Porto criteria’) of the European Society for Ped...
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Article
Open AccessCoexistence of antithrombin deficiency and suspected inferior vena cava atresia in an adolescent and his mother – case report and clinical implications
Antithrombin deficiency (ATD) is an autosomal dominant thrombophilia presenting with varying phenotypes. In pediatric patients with ATD, thrombosis typically develops during the neonatal period or adolescence....
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Article
Open AccessThe role of epigenetic modifications for the pathogenesis of Crohn's disease
Epigenetics has become a promising field for finding new biomarkers and improving diagnosis, prognosis, and drug response in inflammatory bowel disease. The number of people suffering from inflammatory bowel d...
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Article
Erratum zu: Bildgebung chronisch-entzündlicher Darmerkrankungen im Kindes- und Jugendalter. Repetitorium
Ein Erratum zu dieser Publikation wurde veröffentlicht: https://doi.org/10.1007/s00117-020-00755-6
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Article
Bildgebung chronisch-entzündlicher Darmerkrankungen im Kindes- und Jugendalter
Chronisch-entzündliche Darmerkrankungen können bereits im Kindesalter auftreten und manifestieren sich anders als bei Erwachsenen häufiger mit unspezifischen Symptomen. Bei Diagnosestellung liegt oftmals berei...
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Article
Open AccessPReS-FINAL-2332: Activation-induced cell death of human monocytes as a novel mechanism fine-tuning inflammation and autoimmunity
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Open AccessFunctional characterization of GM-CSF induced monocyte subsets
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Article
Open AccessDiagnostic value of 18F-FDG-PET and PET-CT in children with fever of unknown origin or unexplained signs of inflammation
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Article
Open AccessDetection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clam** and hybridisation probes
In the present study, we combined the PCR-clam** approach with melting curve analysis using mutant specific hybridisation probes and wild-type specific peptide nucleic acids (PNAs) to determine the genotypes...