146 Result(s)
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Article
Hyun** Koo
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Open AccessSingle-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis
Periodontitis affects billions of people worldwide. To address relationships of periodontal niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA sequencing (scRNAseq) atla...
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Open AccessInterplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression
Metabolic dysfunction-associated steatotic liver disease (MASLD) is becoming an increasingly pressing global health challenge, with increasing mortality rates showing an upward trend. Two million deaths occur ...
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Open AccessHigh-quality chromosome-level genome assembly of Nicotiana benthamiana
Nicotiana benthamiana is a fundamental model organism in plant research. Recent advancements in genomic sequencing have revealed significant intraspecific genetic variations. This study addresses the pressing nee...
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Open AccessPan-chloroplast genomes for accession-specific marker development in Hibiscus syriacus
Hibiscus syriacus L. is a renowned ornamental plant. We constructed 95 chloroplast genomes of H. syriacus L. cultivars using a short-read sequencing platform (Illumina) and a long-read sequencing platform (Oxford...
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Difference of Weighted Composition Operators Over the Ball
Recently, Choe et al. obtained characterizations for bounded/compact differences of weighted composition operators acting from a standard weighted Bergman space into another over the unit disk. In this paper w...
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Strategy of oversampling geotechnical parameters through geostatistical, SMOTE, and CTGAN methods for assessing susceptibility of landslide
The target slope is generally divided into grids to predict landslide susceptibility; however, it is difficult to acquire all geotechnical properties for each grid. The objective of this study is to examine ov...
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Open AccessHepatocyte GPCR signaling regulates IRF3 to control hepatic stellate cell transdifferentiation
Interferon Regulatory Factor 3 (IRF3) is a transcription factor that plays a crucial role in the innate immune response by recognizing and responding to foreign antigens. Recently, its roles in sterile conditi...
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Open AccessMitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury
Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (WWTR1; also known as TAZ) are the main effectors of the Hippo pathway and their dysregulation contributes to diseases in...
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Open AccessRisk adjustment model for tuberculosis compared to non-tuberculosis mycobacterium or latent tuberculosis infection: Center for Personalized Precision Medicine of Tuberculosis (cPMTb) cohort database
The Center for Personalized Precision Medicine of Tuberculosis (cPMTb) was constructed to develop personalized pharmacotherapeutic systems for tuberculosis (TB). This study aimed to introduce the cPMTb cohort ...
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Open AccessTwo long read-based genome assembly and annotation of polyploidy woody plants, Hibiscus syriacus L. using PacBio and Nanopore platforms
Improvements in long read DNA sequencing and related techniques facilitated the generation of complex eukaryotic genomes. Despite these advances, the quality of constructed plant reference genomes remains rela...
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Sums of Polyanalytic Dual Toeplitz Products
On the setting of the orthogonal complement of the polyanalytic Bergman space of the unit disk, we give characterizations of when a sum of products of several dual Toeplitz operators is compact or zero. Our re...
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Open AccessIron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention
Dental caries is the most common human disease caused by oral biofilms despite the widespread use of fluoride as the primary anticaries agent. Recently, an FDA-approved iron oxide nanoparticle (ferumoxytol, Fe...
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Application of classification coupled with PCA and SMOTE, for obtaining safety factor of landslide based on HRA
Machine learning algorithms have been recently applied to build a landslide susceptibility map. The objective of this study is to find whether classification algorithms of machine learning are suitable for obt...
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Open AccessIdentification of donor Bacteroides vulgatus genes encoding proteins that correlate with early colonization following fecal transplant of patients with recurrent Clostridium difficile
Due to suppressive antibiotics, patients with recurrent Clostridium difficile have gut microbial communities that are devoid of most commensal microbes. Studies have shown that most of the failures using fecal mi...
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Local Hopf Lemma for Certain Degenerate Elliptic Operators on the Half-Space
We prove that the local Hopf lemma of Baouendi–Rothschild for harmonic functions continues to hold for the degenerate elliptic operator, $$\ma...
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Open AccessAddition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities
Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease. Of particular significance, a virulent type of dental caries, known as severe early childhood caries (S-ECC), is characterized by t...
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Open AccessSelenomonas sputigena acts as a pathobiont mediating spatial structure and biofilm virulence in early childhood caries
Streptococcus mutans has been implicated as the primary pathogen in childhood caries (tooth decay). While the role of polymicrobial communities is appreciated, it remains unclear whether other microorganisms are ...
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Open AccessSingle test-based diagnosis of multiple cancer types using Exosome-SERS-AI for early stage cancers
Early cancer detection has significant clinical value, but there remains no single method that can comprehensively identify multiple types of early-stage cancer. Here, we report the diagnostic accuracy of simu...
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Open AccessERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions
Endoplasmic reticulum stress is closely associated with the onset and progression of inflammatory bowel disease. ERdj5 is an endoplasmic reticulum-resident protein disulfide reductase that mediates the cleavag...
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Open AccessApplication of infrared thermography for estimating residual stress in ground anchors for maintenance
Characterizing the integrity of ground anchors is essential for examining their usability in the maintenance of soil structure. However, the lift-off test, which is generally used for this purpose, has limitat...
