-
Article
Open AccessUnraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states
This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Erythematosus (SLE), with a particular focus on those persisting during disease remission.
-
Article
Open AccessAnalysis of characteristic and postexposure practices of occupational blood and body fluid exposures among health care workers in Chinese tertiary hospitals: a retrospective ten-year study
Occupational blood and body fluid exposure (OBEs) is a highly concerning global health problem in health facilities. Improper or inadequate post-exposure practices increase the risk of infection with bloodborn...
-
Article
Open AccessCorrection: Drilling-vibration response characteristics of rocks based on Hilbert–Huang transform
-
Article
Open AccessDrilling-vibration response characteristics of rocks based on Hilbert–Huang transform
Currently, there are no in-situ methods to quantify drilling-vibration response characteristics of different lithologies. Here, we quantified the vibration responses of four lithologies (limestone, sandstone, ...
-
Article
Open AccessTuning transcription factor DegU for develo** extracellular protease overproducer in Bacillus pumilus
Global transcription machinery engineering (gTME) is an effective approach employed in strain engineering to rewire gene expression and reshape cellular metabolic fluxes at the transcriptional level.
-
Article
Open AccessExperimental investigation of the mechanical properties of mud shale under water-bearing conditions and its applications
Mud shale, used in drilling engineering, is prone to hydration and expansion, resulting in creep deformation that leads to wellbore shrinkage and pipe sticking incidents. Studying the creep characteristics of ...
-
Article
Open AccessAlternative autophagy: mechanisms and roles in different diseases
As an important mechanism to maintain cellular homeostasis, autophagy exerts critical functions via degrading misfolded proteins and damaged organelles. Recent years, alternative autophagy, a new type of autop...
-
Article
Open AccessIn situ stress characteristics of the NE Sichuan basin based on acoustic emission test and imaging logging
This study presents the distribution rule of in situ stress in the northeast Sichuan basin and its relationship with fracture. Sixty-seven sets of core samples of 21 Wells from the terrigenous clastic rock for...
-
Article
Open AccessAuthor Correction: Study on discriminant method of rock type for porous carbonate reservoirs based on Bayesian theory
-
Article
Open AccessStudy on discriminant method of rock type for porous carbonate reservoirs based on Bayesian theory
Rock ty** is an extremely critical step in the estimation of carbonate reservoir quality and reserves in the Middle East. In order to recognize the rock types of carbonate reservoirs in the Mishrif Formation...
-
Article
Microstructure and cellular transition characteristic of Ti-42Al-3Nb-1Mo-0.1B alloy
The microstructure and cellular transition characteristics of an intermetallic Ti-42Al-3Nb-1Mo-0.1B (at.%) alloy were investigated. The as-cast microstructure of the alloy is mainly composed of (α2+γ) lamellar st...
-
Article
Open AccessCircular RNA circSLC25A16 contributes to the glycolysis of non-small-cell lung cancer through epigenetic modification
Growing evidence has highlighted the roles of circular RNAs (circRNAs) in non-small-cell lung cancer (NSCLC), however, their roles in NSCLC glycolysis remains poorly understood. CircRNAs microarray profiles di...
-
Article
Open AccessRecombinant expression and biochemical characterization of a novel keratinase BsKER71 from feather degrading bacterium Bacillus subtilis S1-4
Bacillus subtilis S1-4, isolated from chicken feather could efficiently degrade feathers by secreting several extracellular proteases. In order to get insight into the individual protease involved in keratin hydr...
-
Article
Open AccessDisruption of the pleiotropic gene scoC causes transcriptomic and phenotypical changes in Bacillus pumilus BA06
Bacillus pumilus is a Gram-positive and endospore-forming bacterium broadly existing in a variety of environmental niches. Because it produces and secrets many industrially useful enzymes, a lot of studies have b...
-
Article
Open AccessEngineering Bacillus pumilus alkaline serine protease to increase its low-temperature proteolytic activity by directed evolution
Mesophilic alkaline serine proteases from various bacteria have been commercially applied in a range of industries owing to their high catalytic efficiency and wide substrate specificity. However, these protea...
-
Article
Open AccessTranscriptome profiling analysis reveals metabolic changes across various growth phases in Bacillus pumilus BA06
Bacillus pumilus can secret abundant extracellular enzymes, and may be used as a potential host for the industrial production of enzymes. It is necessary to understand the metabolic pr...
-
Article
Open AccessTranscriptome analysis confers a complex disease resistance network in wild rice Oryza meyeriana against Xanthomonas oryzae pv. oryzae
Rice bacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the devastating diseases of rice. It is well established that the wild rice Oryza meyeriana is immune to BB. In this study, the...
-
Article
Open AccessResearch on the relationship between fibrinogen level and subtypes of the TOAST criteria in the acute ischemic stroke
Cerebral infarction caused by different reasons seems differ in fibrinogen levels, so the current work intends to explore the relationship between the fibrinogen level and subtypes of the TOAST criteria in the...
-
Article
Open AccessClinical management of gastric cancer: results of a multicentre survey
The National Comprehensive Cancer Network clinical practice guidelines in oncology-gastric cancer guidelines have been widely used to provide appropriate recommendations for the treatment of patients with gast...