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Open AccessUnraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states
This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Erythematosus (SLE), with a particular focus on those persisting during disease remission.
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Article
Atomization characteristics of pyrolysis oil derived from waste tires
The atomization characteristics play a key role in the highly efficient combustion of pyrolysis oil derived from waste tires. In this study, the fuel properties of tire pyrolysis oil (TPO) were initially studi...
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Open AccessAnalysis of characteristic and postexposure practices of occupational blood and body fluid exposures among health care workers in Chinese tertiary hospitals: a retrospective ten-year study
Occupational blood and body fluid exposure (OBEs) is a highly concerning global health problem in health facilities. Improper or inadequate post-exposure practices increase the risk of infection with bloodborn...
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Open AccessCorrection: Drilling-vibration response characteristics of rocks based on Hilbert–Huang transform
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Open AccessDrilling-vibration response characteristics of rocks based on Hilbert–Huang transform
Currently, there are no in-situ methods to quantify drilling-vibration response characteristics of different lithologies. Here, we quantified the vibration responses of four lithologies (limestone, sandstone, ...
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Article
Open AccessTuning transcription factor DegU for develo** extracellular protease overproducer in Bacillus pumilus
Global transcription machinery engineering (gTME) is an effective approach employed in strain engineering to rewire gene expression and reshape cellular metabolic fluxes at the transcriptional level.
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Article
Precisely map** a major QTL for grain weight on chromosome 5B of the founder parent Chuanmai42 in the wheat-growing region of southwestern China
QTgw.saas-5B was validated as a major thousand-grain weight-related QTL in a founder parent used for wheat breeding and then precisely mapped to a 0.6 cM interval.
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Article
An Improved Method for Predicting Horizontal Principal Stress: A Case Involving a P Gas Field in Northeastern Sichuan
In situ stress is an important parameter in the context of petroleum exploration and development. Triaxial mechanical experiments, acoustic emission analyses, and logging interpretation were performed on sands...
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Article
Open AccessExperimental investigation of the mechanical properties of mud shale under water-bearing conditions and its applications
Mud shale, used in drilling engineering, is prone to hydration and expansion, resulting in creep deformation that leads to wellbore shrinkage and pipe sticking incidents. Studying the creep characteristics of ...
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Creep Mechanical Properties and Constitutive Model of Hard Brittle Mud Shale
Mud shale is characterized by low strength and strong swelling, with rheological effects and deformation caused by drilling fluid and formation water. Establishing a rheological model to characterize the defor...
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Article
Open AccessAlternative autophagy: mechanisms and roles in different diseases
As an important mechanism to maintain cellular homeostasis, autophagy exerts critical functions via degrading misfolded proteins and damaged organelles. Recent years, alternative autophagy, a new type of autop...
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Open AccessIn situ stress characteristics of the NE Sichuan basin based on acoustic emission test and imaging logging
This study presents the distribution rule of in situ stress in the northeast Sichuan basin and its relationship with fracture. Sixty-seven sets of core samples of 21 Wells from the terrigenous clastic rock for...
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Open AccessAuthor Correction: Study on discriminant method of rock type for porous carbonate reservoirs based on Bayesian theory
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Open AccessStudy on discriminant method of rock type for porous carbonate reservoirs based on Bayesian theory
Rock ty** is an extremely critical step in the estimation of carbonate reservoir quality and reserves in the Middle East. In order to recognize the rock types of carbonate reservoirs in the Mishrif Formation...
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Study on origin, classification, and identification of complex porous carbonate reservoir: a case study of the middle cretaceous Mishrif Formation in W Oil field
Based on data of core, thin section, well logging and capillary pressure curves, starting from rock and pore types, reservoir classification is carried out integrating macro and micro perspectives, which can c...
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Article
Microstructure and cellular transition characteristic of Ti-42Al-3Nb-1Mo-0.1B alloy
The microstructure and cellular transition characteristics of an intermetallic Ti-42Al-3Nb-1Mo-0.1B (at.%) alloy were investigated. The as-cast microstructure of the alloy is mainly composed of (α2+γ) lamellar st...
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Article
Characterization of a Protease Hyper-Productive Mutant of Bacillus pumilus by Comparative Genomic and Transcriptomic Analysis
Bacillus pumilus BA06 has great potential for the production of alkaline proteases. To improve the protease yield, classical mutagenesis to combine the physical and chemical mutagens was performed to obtain a pro...
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Article
Radiofrequency ablation versus repeat resection for recurrent hepatocellular carcinoma (≤ 5 cm) after initial curative resection
Recurrence rate is up to 70% at 5 years for hepatocellular carcinoma (HCC) after initial resection, but the management of recurrent HCC remains unclear. To compare the efficacy and safety of radiofrequency abl...
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Article
Open AccessCircular RNA circSLC25A16 contributes to the glycolysis of non-small-cell lung cancer through epigenetic modification
Growing evidence has highlighted the roles of circular RNAs (circRNAs) in non-small-cell lung cancer (NSCLC), however, their roles in NSCLC glycolysis remains poorly understood. CircRNAs microarray profiles di...
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A novel DNA methylation motif identified in Bacillus pumilus BA06 and possible roles in the regulation of gene expression
Single-molecule real-time (SMRT) sequencing can be used to identify a wide variety of chemical modifications of the genome, such as methylation. Here, we applied this approach to identify N6-methyl-adenine (m6...