13 Result(s)

Article

Comparison of the prognostic impact of IPI and PIT in peripheral T-cell lymphoma in real-world practice with a large elderly population

We compared the predictive ability of the International Prognostic Index (IPI), a frequently used prognostic model for peripheral T-cell lymphoma (PTCL), with that of a type-specific prognostic model, the Prog...

Nobuhiko Nakamura, Nobuhiro Kanemura, Takuro Matsumoto… in Scientific Reports (2023)

Article

Assessment of satisfaction with antiretroviral drugs and the need for long-acting injectable medicines among people living with HIV in Japan and its associated factors: a prospective multicenter cross-sectional observational study

Long-acting injectable formulations for HIV infection have been approved and are now available in Japan. Although not currently recommended as first-line drugs in Japanese or overseas guidelines, use of such f...

Masashi Ishihara, Shinichi Hikasa, Mariko Tsukiji… in AIDS Research and Therapy (2023)

Article

Prognostic value of metabolic tumor volume of extranodal involvement in diffuse large B cell lymphoma

Extranodal involvement predicts poor outcomes of diffuse large B cell lymphoma (DLBCL), but the impact of the metabolic tumor burden (MTV) of extranodal sites using positron emission tomography has not been cl...

Kana Oiwa, Kei Fujita, Shin Lee, Tetsuji Morishita… in Annals of Hematology (2023)

Article

A multicenter phase II study of bendamustine, rituximab, and cytarabine (BRAC) for relapsed or refractory patients with follicular lymphoma or mantle cell lymphoma

This phase II clinical trial aimed to evaluate the efficacy and safety of the combination therapy of bendamustine, cytarabine, and rituximab (BRAC) in patients with relapsed or refractory follicular lymphoma (...

Nobuhiko Nakamura, Senji Kasahara, Junichi Kitagawa… in Experimental Hematology & Oncology (2022)

Article

Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Elsa Bernard, Yasuhito Nannya, Robert P. Hasserjian, Sean M. Devlin… in Nature Medicine (2021)

Article

Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

A Correction to this paper has been published: https://doi.org/10.1038/s41591-021-01253-5.

Elsa Bernard, Yasuhito Nannya, Robert P. Hasserjian, Sean M. Devlin… in Nature Medicine (2021)

Article

Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling

Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) is a diagnosis of exclusion, being the most common entity in mature T-cell neoplasms, and its molecular pathogenesis remains significantly unders...

Yosaku Watatani, Yasuharu Sato, Hiroaki Miyoshi, Kana Sakamoto, Kenji Nishida… in Leukemia (2019)

Article

Plasma concentrations of dasatinib have a clinical impact on the frequency of dasatinib dose reduction and interruption in chronic myeloid leukemia: an analysis of the DARIA 01 study

Dasatinib has shown promising anti-leukemic activity against chronic myeloid leukemia (CML). However, patients receiving dasatinib frequently require dose reductions and treatment interruptions (treatment alte...

Shuichi Mizuta, Masashi Sawa, Hisashi Tsurumi… in International Journal of Clinical Oncology (2018)

Article

Preparation and clinical evaluation of a novel lozenge containing polaprezinc, a zinc-L-carnosine, for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy

We previously reported that oral ingestion of polaprezinc, a zinc-L-carnosine, suspended in sodium alginate solution prevents oral mucositis in patients receiving radiotherapy or high-dose chemotherapy. In the...

Hiroko Hayashi, Ryo Kobayashi, Akio Suzuki, Yuto Yamada… in Medical Oncology (2016)

Article

(—)-Epigallocatechin-3-gallate suppresses hepatic preneoplastic lesions developed in a novel rat model of non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis to non-alcoholic steatohepatitis (NASH). NASH, which is accompanied by increased oxidative stress and inflammation in the liver, is associ...

Takafumi Sumi, Yohei Shirakami, Masahito Shimizu, Takahiro Kochi… in SpringerPlus (2013)

Article

Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells

A malfunction of RXRα due to phosphorylation is associated with liver carcinogenesis, and acyclic retinoid (ACR), which targets RXRα, can prevent the development of hepatocellular carcinoma (HCC). Activation o...

Atsushi Baba, Masahito Shimizu, Tomohiko Ohno, Yohei Shirakami, Masaya Kubota… in BMC Cancer (2013)

Article

Pitavastatin suppresses diethylnitrosamine-induced liver preneoplasms in male C57BL/KsJ-db/dbobese mice

Obesity and related metabolic abnormalities, including inflammation and lipid accumulation in the liver, play a role in liver carcinogenesis. Adipocytokine imbalances, such as decreased serum adiponectin level...

Masahito Shimizu, Yoichi Yasuda, Hiroyasu Sakai, Masaya Kubota… in BMC Cancer (2011)

Article

Correction

Hisashi Tsurumi, Shigefumi Okada, Yasukazu Koshino… in Gastroenterologia Japonica (1991)