32 Result(s)

Article

Safe administration of rituximab for follicular lymphoma after obinutuzumab infusion-related reaction

Obinutuzumab is a novel glycoengineered, type-II anti-CD20 monoclonal antibody that was recently developed to treat follicular lymphoma (FL), the most prevalent subtype of indolent B-cell lymphoma. Several int...

Takeshi Hara, Ryohei Suzuki, Akihisa Ohno… in International Journal of Hematology (2020)

Article

Follicular lymphoma suggested to transform into EBV-negative plasmablastic lymphoma

Follicular lymphoma (FL) is an indolent lymphoma that often transforms into a high-grade lymphoma, mostly diffuse large B-cell lymphoma. A case of FL suggested to transform into plasmablastic lymphoma is prese...

Toshiki Yamada, Takeshi Hara, Naoe Goto… in International Journal of Hematology (2019)

Article

Prognostic impact of skeletal muscle assessed by computed tomography in patients with acute myeloid leukemia

Skeletal muscle atrophy and loss of adipose tissue, referred to as sarcopenia and adipopenia, respectively, are often observed in cancer patients. We investigated the impact of sarcopenia and adipopenia on cli...

Nobuhiko Nakamura, Soranobu Ninomiya, Takuro Matsumoto… in Annals of Hematology (2019)

Article

Efficacy of upfront high-dose chemotherapy plus rituximab followed by autologous peripheral blood stem cell transplantation for untreated high-intermediate-, and high-risk diffuse large B-cell lymphoma: a multicenter prospective phase II study (JSCT-NHL04)

To evaluate the efficacy and feasibility of upfront high-dose chemotherapy (HDCT) and rituximab (R) followed by autologous peripheral blood stem cell transplantation (auto-PBSCT) in patients with newly diagnos...

Tohru Murayama, Takahiro Fukuda, Hirokazu Okumura… in International Journal of Hematology (2016)

Article

Multiple myeloma with Russell bodies and needle-shaped crystalline inclusions

Toshiki Yamada, Yasuhito Nannya, Naoki Mita… in International Journal of Hematology (2016)

Article

Sarcopenia is an independent prognostic factor in male patients with diffuse large B-cell lymphoma

Sarcopenia reportedly predicts poor outcomes in elderly patients with diffuse large B-cell lymphoma (DLBCL). However, because previous studies only involved elderly patients, it is difficult to generalize thes...

Nobuhiko Nakamura, Takeshi Hara, Yuhei Shibata, Takuro Matsumoto… in Annals of Hematology (2015)

Article

Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice

Indoleamine 2,3-dioxygenase (IDO) catalyzes the rate-limiting step in the metabolism of tryptophan along the kynurenine pathway. In tumors, increased IDO activity inhibits proliferation and induces apoptosis o...

Nobuhiko Nakamura, Takeshi Hara, Masahito Shimizu… in International Journal of Hematology (2015)

Article

Clinical significance of jejunoileal involvement of non-Hodgkin’s lymphoma detected by double-balloon enteroscopy

Jejunoileal involvement of non-Hodgkin’s lymphoma (NHL) is an important diagnostic factor in determining optimal treatment strategies. Here, we used double-balloon enteroscopy (DBE) to detect jejunoileal invol...

Takashi Ibuka, Hisashi Tsurumi, Hiroshi Araki… in International Journal of Hematology (2013)

Article

Cerebriform variant type of T cell prolymphocytic leukemia with complex karyotype including an additional segment at 1p36.1

We describe two patients with T cell prolymphocytic leukemia (T-PLL) who exhibited the same complex karyotype, including an additional segment at 1p36.1. One presented with secondary progression following an i...

Senji Kasahara, Hisashi Tsurumi, Yuhei Shibata… in International Journal of Hematology (2012)

Article

Extravascular hemolytic attack after eculizumab therapy for paroxysmal nocturnal hemoglobinuria

Akihiro Tomita, Yukari Shirasugi, Takahiko Ito, Hisashi Tsurumi… in Annals of Hematology (2012)

Article

First report of drug-induced esophagitis by deferasirox

Deferasirox is a new oral iron chelator used to treat transfusional iron overload. We describe a case of a 79-year-old man with myelodysplastic syndrome (MDS) who developed esophagitis induced by deferasirox. ...

Takeshi Yoshikawa, Takeshi Hara, Hiroshi Araki… in International Journal of Hematology (2012)

Article

Serum soluble interleukin-2 receptor (sIL-2R) level is associated with the outcome of patients with diffuse large B cell lymphoma treated with R-CHOP regimens

Serum concentration of soluble interleukin-2 receptor (sIL-2R) predicts the clinical outcome of patients with aggressive non-Hodgkin's lymphoma treated with the cyclophosphamide, doxorubicin, vincristine, and ...

Naoe Goto, Hisashi Tsurumi, Hideko Goto, Yoriko Ino Shimomura… in Annals of Hematology (2012)

Article

Coexistence of inversion 16 and the Philadelphia chromosome comprising P190 BCR/ABL in chronic myeloid leukemia blast crisis

A 63-year-old woman presented with leukocytosis (278 × 10⁹/L) with 72% blasts. Bone marrow blast cells showed cytogenetic abnormality with 46,XX, t(9;22), inv(16). Despite achievement of hematological remission b...

Soranobu Ninomiya, Nobuhiro Kanemura… in International Journal of Hematology (2011)

Article

Synergistic growth inhibition in HL-60 cells by the combination of acyclic retinoid and vitamin K₂

The aim of this study was to assess the effects of acyclic retinoid (ACR) and vitamin K₂ (VK₂) in HL-60 cells.

Junichi Kitagawa, Takeshi Hara… in Journal of Cancer Research and Clinical On… (2011)

Article

Indoleamine 2,3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP

Indoleamine 2,3-dioxygenase (IDO) exerts immunomodulatory effects due to enzymatic activities catalyzing the essential amino acid l-tryptophan. IDO activity might play an important role in regulating immune respo...

Soranobu Ninomiya, Takeshi Hara, Hisashi Tsurumi, Masato Hoshi… in Annals of Hematology (2011)

Article

Phase II study of Rituximab combined with THP-COP as first-line therapy for patients younger than 70 years with diffuse large B cell lymphoma

We previously described the effectiveness of the THP-COP regimen comprising cyclophosphamide, pirarubicin (tetrahydropyranyl adriamycin; THP), vincristine and prednisolone in patients with diffuse large B-cell...

Takeshi Hara, Hisashi Tsurumi, Naoe Goto… in Journal of Cancer Research and Clinical On… (2010)