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Article
Modulation of poly(β-amino ester) pH-sensitive polymers by molecular weight control
The main objective of this study was to modulate pH-sensitive polymers(poly(β-amino esters)) by controlling their molecular weight during their synthesis. These pH-sensitive and biodegradable polymers were syn...
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Article
Transferrin-conjugated liposome/IL-12 pDNA complexes for cancer gene therapy in mice
Transferrin (Tf) has been used as a targeting ligand for delivering liposome/interleukin-12 (IL-12) pDNA complexes to cancer cells mostly due to the greater number of transferrin receptors (TfR) found on tumor ce...
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Article
pH-sensitivity control of PEG-poly(β-amino ester) block copolymer micelle
Poly(ethylene glycol) methyl ether (PEG)-poly(β-amino ester) (PAE) block copolymers were synthesized using a Michael-type step polymerization, and the construction of pH-sensitive polymeric micelles (PM) inves...