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Article
Difference in formation mechanism of inclusion complex between configuration isomers of gallate-type catechin and β-cyclodextrin
The formation mechanism of inclusion complex between (-)-epigallocatechin gallate (EGCg), which is the main catechin in tea leaves, or (-)-gallocatechin gallate (GCg), which is an isomer of EGCg, and β-cyclode...
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Article
Effect of solution pH on complex formation between epi-type catechin and β-cyclodextrin
The effect of solution pH on the formation of an inclusion complex between (−)-epigallocatechin gallate (EGCg: pKa = 7.5) and β-cyclodextrin (β-CD) was investigated by isothermal titration calorimetry and 1H-NMR ...
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Article
Carbohydrate recognition of C3-symmetrical tripodal receptor-type 2,4,6-trisubstituted 1,3,5-triazine derivatives with antiviral activities
In our search for new bioactive compounds that interfere with the sugar recognition process, we have designed and synthesized C3- and Cs-symmetrical tripodal receptor-type molecules. Among the synthesized C3-symm...
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Article
Recent advances in calorimetry and thermal analysis: Collected papers from the 8th international and 10th Japan–China joint symposium on calorimetry and thermal analysis (CATS-2017)
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Article
Improving water solubility of nateglinide by complexation of β-cyclodextrin
Inclusion complex of anionic nateglinide (NTG) with β-cyclodextrin (βCD) has been prepared to improve the water solubility of NTG. The mechanism of the complexation was elucidated using isothermal titration ca...
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Article
Carbohydrate recognition of symmetrical tripodal receptor type tris(2-aminoethyl)amine derivatives
Carbohydrate recognition of some bioactive symmetrical tripodal receptor type tris(2-aminoethyl)amine (TAEA) derivatives was investigated. In calorimetric experiments, the highest binding constant (Ka) of compoun...
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Article
Drug–tea polyphenol interaction
Propericiazine (PCZ) is an antipsychotic agent used for the treatment and the prevention of relapse of schizophrenia. We found that when an oral solution containing PCZ was mixed with a green tea drink, the re...