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Article
Correlation of hepatitis B virus, hepatitis D virus and human immunodeficiency virus type I infection markers in hepatitis B surface antigen positive haemophiliacs and patients without haemophilia with clinical and histopathological outcome of hepatitis
The hepatitis D virus (HDV) infection plays a major role in severe liver damage caused by hepatitis. To establish the prevalence of HDV infection in haemophilic patients and patients without haemophilia, 87 pa...
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Article
25 Hydroxyvitamin D and vitamin E absorption in healthy children and children with chronic intrahepatic cholestasis
Patients with chronic cholestasis have reduced 25-hydroxyvitamin D (25 OHD) and vitamin E levels. We determined serum concentrations of 25 OHD, 1,25-dihydroxyvitamin D [1,25(OH)2D] and vitamin E before and after ...
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Article
Serum immunoreactive trypsin and pancreatic lipase in cystic fibrosis
Serum immunoreactive trypsin (IRT) and pancreatic lipase have been measured in 59 patients with cystic fibrosis (age 1 month-27 years). Follow-up values were obtained from 49 patients. Their serum enzyme level...
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Article
Biliary lipid metabolism in children with chronic intrahepatic cholestasis
Biliary lipid composition, standard liver function tests, serum lipids and faecal fat excretion were studied in 15 children with chronic intrahepatic cholestasis (severe intrahepatic cholestasis, n=6; paucity of ...
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Article
Effects of phenobarbital on biliary lipid metabolism in children with chronic intrahepatic cholestasis
The effects of phenobarbital (5.4–7.5 mg/kg body weight) for 14 days were studied in four children with severe intrahepatic cholestasis (group I) and in four with a syndromatic type of paucity of intralobular ...
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Article
Chronic viral hepatitis B in childhood
The results of immunological studies in serum and liver tissue from 26 patients with chronic HBsAg-positive hepatitis (15 CPH, 9 CAH, 2 MinH) are presented.
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Article
Chronic viral hepatitis B in childhood
The results of clinical, biochemical and histological studies in 26 children with chronic hepatitis B are reported.
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Article
Cyclic AMP in pancreatic and biliary secretion of children with chronic intrahepatic cholestasis and cystic fibrosis
The intracellular transmitter cAMP enters the extracellular space and can be found in the duodenal fluid. The role of this messenger was investigated in response to secretin and CCK in children with secretory ...
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Article
Complement studies in children with treated coeliac disease after gluten challenge
Changes of the complement components in the sera of 13 children with treated coeliac disease were studied after gluten challenge. The levels of C 1 and C 3-activator (factor B) were significantly decreased at ...
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Article
Selective vitamin B12 malabsorption (Imerslund-Gräsbeck Syndrome)
In a girl 10 years of age with selective vitamin B12 malabsorption associated with proteinuria and residual symptoms of funicular myelosis an extensive study of the intestinal and nephrologic functions was done. ...
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Article
Serum alpha1-fetoprotein in cystic fibrosis
In 38 children and adolescents with cystic fibrosis, in 19 normal children and 62 healthy adults the serum α1-fetoprotein concentrations were measured by radioimmunoassay. In cystic fibrosis patients 97.5% and in...
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Article
151: Composition of brush border membranes in several congenital intestinal enzyme deficiencies investigated by use of SDS-polyacrylamide-gel-electrophoresis
1. In 3 children with congenital lactose malabsorption and 2 adults with specific hypolactasia a reduction of the glycoprotein band corresponding to brush border lactase was found. The protein band was reduced...
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Article
Antiretikulin-Antikörper und präcipitierende Antikörper gegen Nahrungsmittelproteine im Serum von Kindern mit Cöliakie
Sera from 41 children suffering with histologically proven coeliac disease and from 40 healthy control children were investigated for the presence of antireticulin antibodies and precipitating antibodies to a ...
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Article
Hypertension und Nierenarterienstenose bei Hyperlipidämie durch kongenitale intrahepatische Gallengangshypoplasie
Report of a 10-year-old boy with congenital hypoplasia of the intrahepatic bile ducts, the socalled MacMahon-Thannhauser-Syndrome. The patient had been suffering from a varying degree of jaundice since his 2nd...
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Article
Vitamin A, Carotin, retinolbindendes Protein und Präalbumin im Serum von Patienten mit cystischer Fibrose
Vitamin A, carotene, retinol-binding protein (RBP), and prealbumin (PA) have been measured in 42 children and adolescents with cystic fibrosis (CF) and in 92 normal controls. All patients with CF were on vitam...
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Article
Identifizierung heterozygoter Genträgerinnen der rasch progredienten recessiv X-chromosomalen Muskeldystrophie (Typ Duchenne)
SH-activated serum-CPK has been estimated in 84 carriers of X-linked muscular dystrophy type Duchenne. The series includes 6 definite, 5 probable and 73 possible carriers. In 83% of the definite, 60% of the pr...
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Article
Neuer Typ einer recessiv X-chromosomal vererbten Muskeldystrophie: Scapulo-humero-distale Muskeldystrophie mit frühzeitigen Kontrakturen und Herzrhythmusstörungen
A kinship living in lower Bavaria (Germany) is described with a distinct type of a recessive X-linked muscular dystrophy. The disease was observed in 3 generations affecting 17 males. Among the earliest manife...
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Article
Trennung der intestinalen β-Galactosidasen beim lactose-toleranten Erwachsenen durch Ultrazentrifugation im Dichtegradienten
The intestinalβ-galactosidases in suction biopsy material of 4 lactose-tolerant adult Europeans were separated after solubilization with Triton X-100 in a linear 5–20% mannitol gradient by ultracentrifugation at ...
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Article
Trennung der intestinalen β-Galactosidasen beim lactose-intoleranten Erwachsenen durch Ultrazentrifugation im Dichtegradienten
In 11 adult probands with lactose intolerance the intestinalβ-galactosidases were separated in a density gradient by ultracentrifugation. The “neutral” brush border lactase and the “acid” lysosomal lactase were i...
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Article
Lactose intolerance in Arabs
A high incidence (minimum 20/26, maximum 24/26) of lactose intolerance was found in a group of adult Arab subjects. A selective reduction of intestinallactase activity was present in 4 subjects in whom a sucti...