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Article
Open AccessGene-by-environment interactions in urban populations modulate risk phenotypes
Uncovering the interaction between genomes and the environment is a principal challenge of modern genomics and preventive medicine. While theoretical models are well defined, little is known of the G × E inter...
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Article
Open AccessGENLIB: an R package for the analysis of genealogical data
Founder populations have an important role in the study of genetic diseases. Access to detailed genealogical records is often one of their advantages. These genealogical data provide unique information for res...
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Article
Open AccessOn the proportional hazards model for occupational and environmental case-control analyses
Case-control studies are generally designed to investigate the effect of exposures on the risk of a disease. Detailed information on past exposures is collected at the time of study. However, only the cumulate...