3 Result(s)
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Article
Gonzalo del Monte-Nieto
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Article
Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation
In vertebrate hearts, the ventricular trabecular myocardium develops as a sponge-like network of cardiomyocytes that is critical for contraction and conduction, ventricular septation, papillary muscle formatio...
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Article
Open AccessUncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1
Coronary artery anomalies may cause life-threatening cardiac complications; however, developmental mechanisms underpinning coronary artery formation remain ill-defined. Here we identify an angiogenic cell popu...
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Article
Sequential Notch activation regulates ventricular chamber development
Ventricular chambers are essential for the rhythmic contraction and relaxation occurring in every heartbeat throughout life. Congenital abnormalities in ventricular chamber formation cause severe human heart d...
