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  1. No Access

    Article

    Automated high-speed 3D imaging of organoid cultures with multi-scale phenotypic quantification

    Current imaging approaches limit the ability to perform multi-scale characterization of three-dimensional (3D) organotypic cultures (organoids) in large numbers. Here, we present an automated multi-scale 3D im...

    Anne Beghin, Gianluca Grenci, Geetika Sahni, Su Guo, Harini Rajendiran… in Nature Methods (2022)

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    Article

    Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device

    This protocol describes a microfluidics approach for culturing liquid-biopsy-derived circulating tumor cell clusters to predict a patient's response toward various therapeutic strategies.

    Bee Luan Khoo, Gianluca Grenci, Ying Bena Lim, Soo Chin Lee… in Nature Protocols (2018)

  3. No Access

    Article

    3D high- and super-resolution imaging using single-objective SPIM

    Light-sheet microscopy using a single objective and micromirrors to orient the light sheet enables high- and super-resolution imaging of cells and embryos on a standard microscope.

    Remi Galland, Gianluca Grenci, Ajay Aravind, Virgile Viasnoff… in Nature Methods (2015)