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  1. Article

    Open Access

    Career destinations of graduates from a medical school with an 18-week longitudinal integrated clerkship in general practice: a survey of alumni 6 to 8 years after graduation

    There is a worldwide recruitment and retention crisis in general practice. Workforce planning has identified the need to train more general practitioners as an urgent priority. Exposure of medical students to ...

    Liam G. Glynn, Andrew O. Regan, Monica Casey… in Irish Journal of Medical Science (1971 -) (2021)

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  2. Article

    Open Access

    The University of Limerick Education and Research Network for General Practice (ULEARN-GP): practice characteristics and general practitioner perspectives

    A well-functioning general practice sector that has a strong research component is recognised as a key foundation of any modern health system. General practitioners (GPs) are more likely to collaborate in rese...

    Andrew O’Regan, Peter Hayes, Ray O’Connor, Monica Casey, Pat O’Dwyer… in BMC Family Practice (2020)

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  3. No Access

    Article

    The dopamine D2 receptor partial agonist aplindore improves motor deficits in MPTP-treated common marmosets alone and combined with l-dopa

    Dopamine replacement therapy in Parkinson’s disease (PD) using l-dopa is invariably associated with a loss of drug efficacy (“wearing off”) and the onset of dyskinesia. The use of dopamine receptor partial agonis...

    Michael John Jackson, Terrance H. Andree, Matthew Hansard… in Journal of Neural Transmission (2010)

  4. No Access

    Article

    WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics

    5-HT2C agonists, by decreasing mesolimbic dopamine without affecting nigrostriatal dopamine, are predicted to have antipsychotic efficacy with low extrapyramidal side effects (EPS). Combining 5-HT2C agonists with...

    Steven M. Grauer, Radka Graf, Rachel Navarra, Amy Sung… in Psychopharmacology (2009)

  5. No Access

    Article

    Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents

    Activation of one or more of the serotonin (5-HT) receptors may play a role in mediating the antidepressant effects of SSRIs.

    Sharon Rosenzweig-Lipson, Annmarie Sabb, Gary Stack, Paul Mitchell… in Psychopharmacology (2007)