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Article
Rescue of oxytocin response and social behaviour in a mouse model of autism
A fundamental challenge in develo** treatments for autism spectrum disorders is the heterogeneity of the condition. More than one hundred genetic mutations confer high risk for autism, with each individual m...
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Article
Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics
GABAB receptors are the most abundant inhibitory G protein–coupled receptors in the mammalian brain. Using high-resolution proteomics, the authors show that native GABAB receptors are macromolecular complexes wit...
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Article
Dendritic encoding of sensory stimuli controlled by deep cortical interneurons
Dendrites enhance the computational power of neurons by active processing of synaptic inputs but their activity, particularly in cortex, has been hard to measure. Matthew Larkum and colleagues now use a new fi...