6 Result(s)
within
English
Life Sciences
Computational Biology/Bioinformatics
Computer Appl. in Life Sciences
Microarrays
Edda Klipp
Article
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Article
Open Accesskboolnet: a toolkit for the verification, validation, and visualization of reaction-contingency (rxncon) models
Computational models of cell signaling networks are extremely useful tools for the exploration of underlying system behavior and prediction of response to various perturbations. By representing signaling casca...
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Article
Open AccessPropagating semantic information in biochemical network models
To enable automatic searches, alignments, and model combination, the elements of systems biology models need to be compared and matched across models. Elements can be identified by machine-readable biological ...
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Article
Open AccessSTSE: Spatio-Temporal Simulation Environment Dedicated to Biology
Recently, the availability of high-resolution microscopy together with the advancements in the development of biomarkers as reporters of biomolecular interactions increased the importance of imaging methods in...
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Article
Open AccessTIde: a software for the systematic scanning of drug targets in kinetic network models
During the stages of the development of a potent drug candidate compounds can fail for several reasons. One of them, the efficacy of a candidate, can be estimated in silico if an appropriate ordinary differential...
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Article
Open AccessTowards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation
The cell cycle is a complex process that allows eukaryotic cells to replicate chromosomal DNA and partition it into two daughter cells. A relevant regulatory step is in the G0/G1 phase, a point called the restric...
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Article
Open AccessSBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool
It has long been recognized that sensitivity analysis plays a key role in modeling and analyzing cellular and biochemical processes. Systems biology markup language (SBML) has become a well-known platform for ...
