18 Result(s)

Article

New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis

Bone marrow-derived mesenchymal stem cell (_BMMSC)-based therapy has become a major focus for treating liver fibrosis/cirrhosis. However, although these cell therapies promote the treatment of this disease, the he...

Deyu Hu, Jiejuan Lai, Quanyu Chen, Lianhua Bai in Stem Cell Research & Therapy (2024)

Article

CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity

cGAS/DncV-like nucleotidyltransferase (CD-NTase) family members are immune sensors that synthesize diverse nucleotide signals to initiate antiviral response in bacteria and animals. As a founding member of CD-...

Hansen Liu, Zhenzhen Yan, Deyu Zhu, Haiyan Xu, Feng Liu… in Cell Death & Differentiation (2023)

Article

NtMYB12 requires for competition between flavonol and (pro)anthocyanin biosynthesis in Narcissus tazetta tepals

The color of flowers is one of the main characteristics adopted for plants to attract pollinators to ensure the reproductive success of the plant, they are also important in their ornamental appeal in Narcissus p...

**gwen Yang, ** Wu, Cristina belen Aucapiña, Deyu Zhang… in Molecular Horticulture (2023)

Article

Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8⁺ T cells in normal and cirrhotic livers

Intrahepatic stem/progenitor cells and cytotoxic CD8⁺ T cells (CD8⁺ T cells) in the cirrhotic liver undergo apoptosis, which potentially facilitates progression to cancer. Here, we report that hepatocyte growth f...

Quanyu Chen, Min Yan, Heng Lin, Jiejuan Lai, Zhiqing Yang, Deyu Hu… in Cell Death Discovery (2023)

Article

An updated RBD-Fc fusion vaccine booster increases neutralization of SARS-CoV-2 Omicron variants

Deyan Luo, **aolan Yang, Tao Li, Nianzhi Ning… in Signal Transduction and Targeted Therapy (2022)

Article

Correction to: DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis

A Correction to this paper has been published: https://doi.org/10.1038/s41418-021-00736-9

Menglang Yuan, **nsheng Zhang, **gbo Zhang, Keyong Wang… in Cell Death & Differentiation (2022)

Article

Aptamer blocking S-TLR4 interaction selectively inhibits SARS-CoV-2 induced inflammation

Gang Yang, Shengnan Zhang, Yuchun Wang, Ling Li… in Signal Transduction and Targeted Therapy (2022)

Article

Identification of critical pathways and potential therapeutic targets in poorly differentiated duodenal papilla adenocarcinoma

Duodenal papilla carcinoma (DPC) is a rare malignancy of the gastrointestinal tract with high recurrence rate, and the pathogenesis of this highly malignant neoplasm is yet to be fully elucidated. This study a...

Yuanxiang Lu, Wensen Li, Ge Liu, Yongbo Yang, Erwei **ao… in Cancer Cell International (2021)

Article

miR-362-5p promotes cell proliferation and cell cycle progression by targeting GAS7 in acute myeloid leukemia

Recently, miR-362-5p has attracted special interest as a novel prognostic predictor in acute myeloid leukemia (AML). However, its biological function and underlying molecular mechanism in AML remain to be furt...

Fuqun Wu, Changxin Yin, Junhua Qi, Deyu Duan, ** Jiang, Jianhua Yu… in Human Cell (2020)

Article

DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis

DC-SIGN is previously focused on its physiologic and pathophysiologic roles in immune cells. Little is known about whether DC-SIGN is expressed in malignant epithelial cells and how DC-SIGN participates in tum...

Menglang Yuan, **nsheng Zhang, **gbo Zhang, Keyong Wang… in Cell Death & Differentiation (2020)

Article

MicroRNA-153-3p enhances cell radiosensitivity by targeting BCL2 in human glioma

Glioma is the most prevalent malignant tumor in human central nervous systems. Recently, the development of resistance to radiotherapy in glioma patients markedly vitiates the therapy outcome. MiR-153-3p has b...

Deyu Sun, Yi Mu, Haozhe Piao in Biological Research (2018)

Article

The PilZ domain of MrkH represents a novel DNA binding motif

Feng Wang, Qing He, Kaixuan Su, Fei Gao, Yan Huang, Zong Lin, Deyu Zhu… in Protein & Cell (2016)

Article

PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix

Biofilms are surface-associated communities of microorganism embedded in extracellular matrix. Exopolysaccharide is a critical component in the extracellular matrix that maintains biofilm architecture and prot...

Shan Yu, Tiantian Su, Huijun Wu, Shiheng Liu, Di Wang, Tianhu Zhao… in Cell Research (2015)

Article

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1

The elevated level of CCNB1 indicates more aggressive cancer and poor prognosis. However, the factors that cause CCNB1 upregulation remain enigmatic. Herein, we identify USP22 as a CCNB1 interactor and discove...

Zhenghong Lin, Can Tan, Quan Qiu, Sinyi Kong, Heeyoung Yang, Fang Zhao… in Cell Discovery (2015)

Article

A novel ER–microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression

The gene encoding endoplasmic reticulum (ER) lipid raft-associated protein 2 (ERLIN2) is amplified in human breast cancers. ERLIN2 gene mutations were also found to be associated with human childhood progressive ...

Xuebao Zhang, Juan Cai, Ze Zheng, Lisa Polin, Zhenghong Lin… in Cell Discovery (2015)

Article

Neurovascular unit on a chip: implications for translational applications

The blood-brain barrier (BBB) dynamically controls exchange between the brain and the body, but this interaction cannot be studied directly in the intact human brain or sufficiently represented by animal model...

Donald J Alcendor, Frank E Block III, David E Cliffel… in Stem Cell Research & Therapy (2013)

Article

Antiproliferative and cell apoptosis-inducing activities of compounds from Buddleja davidii in Mgc-803 cells

Buddleja davidii is widely distributed in the southwestern region of China. We have undertaken a systematic analysis of B. davidii as a Chinese traditional medicine with anticancer activity by isolating natural ...

Jian Wu, Wenshi Yi, Linhong **, Deyu Hu, Baoan Song in Cell Division (2012)

Article

Antiproliferation and cell apoptosis inducing bioactivities of constituents from Dysosma versipellis in PC3 and Bcap-37 cell lines

Recently, interest in phytochemicals from traditional Chinese medicinal herbs with the capability to inhibit cancer cells growth and proliferation has been growing rapidly due to their nontoxic nature. Dysosma ve...

**aoqiang Xu, **uhong Gao, Linhong **, Pinaki S Bhadury, Kai Yuan… in Cell Division (2011)