Skip to main content

11 Result(s)

within Article Remove this filter Cristina Marzano Remove this filter

and

  1. No Access

    Article

    Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes

    Four estrogen-functionalised copper complexes were synthesised and investigated as electrochemical active DNA binding and cleavage agents. These complexes strategically contain a biocompatible metal centre [Cu...

    Stephen Barrett, Michele De Franco… in JBIC Journal of Biological Inorganic Chemi… (2020)

  2. Article

    Open Access

    Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors

    [Cu(thp)4][PF6] (HydroCuP) is a phosphino copper(I) complex highly soluble and stable in physiological media that has been developed as a possible viable alternative to platinum-based drugs for anticancer therapy...

    Valentina Gandin, Cecilia Ceresa, Giovanni Esposito… in Scientific Reports (2017)

    Download PDF (5593 KB) View Article

  3. No Access

    Article

    Predicting Dream Recall: EEG Activation During NREM Sleep or Shared Mechanisms with Wakefulness?

    The common knowledge of a uniqueness of REM sleep as a privileged scenario of dreaming still persists, although consolidated empirical evidence shows that the assumption that dreaming is just an epiphenomenon of ...

    Serena Scarpelli, Aurora D’Atri, Anastasia Mangiaruga, Cristina Marzano… in Brain Topography (2017)

  4. Article

    Open Access

    Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates

    We present the anticancer properties of cis, cis, trans-[Pt(IV)(NH3)2Cl2(OA)2] [Pt(IV)diOA] (OA = octanoato), Pt(IV) derivative of cisplatin containing two OA units appended to the axial positions of a six-coordi...

    Vojtech Novohradsky, Ilaria Zanellato, Cristina Marzano… in Scientific Reports (2017)

    Download PDF (2030 KB) View Article

  5. Article

    Open Access

    Oxidative Stress Induced by Pt(IV) Pro-drugs Based on the Cisplatin Scaffold and Indole Carboxylic Acids in Axial Position

    The use of Pt(IV) complexes as pro-drugs that are activated by intracellular reduction is a widely investigated approach to overcome the limitations of Pt(II) anticancer agents. A series of ten mono- and bis-c...

    Dina Tolan, Valentina Gandin, Liam Morrison, Ahmed El-Nahas… in Scientific Reports (2016)

    Download PDF (1780 KB) View Article

  6. Article

    Open Access

    Targeting kinases with anilinopyrimidines: discovery of N-phenyl-N’-[4-(pyrimidin-4-ylamino)phenyl]urea derivatives as selective inhibitors of class III receptor tyrosine kinase subfamily

    Kinase inhibitors are attractive drugs/drug candidates for the treatment of cancer. The most recent literature has highlighted the importance of multi target kinase inhibitors, although a correct balance betwe...

    Valentina Gandin, Alessandro Ferrarese, Martina Dalla Via… in Scientific Reports (2015)

    Download PDF (4347 KB) View Article

  7. No Access

    Article

    99mTc(N)-DBODC(5), a potential radiolabeled probe for SPECT of multidrug resistance: in vitro study

    [99mTc(N)(DBODC)(PNP5)]+ [DBODC is bis(N-ethoxyethyl)dithiocarbamato; PNP5 is bis(dimethoxypropylphosphinoethyl)ethoxyethylamine], abbreviated as 99mTc(N)-DBODC(5), is a lipophilic cationic mixed compound investi...

    Cristina Bolzati, Davide Carta… in JBIC Journal of Biological Inorganic Chemi… (2013)

  8. No Access

    Article

    Validity of the Italian Version of the Pittsburgh Sleep Quality Index (PSQI)

    The aim of this study is to validate the Italian version of the Pittsburgh Sleep Quality Index (PSQI), comparing five different groups of individuals (healthy young and elderly, sleep apnoea syndrome patients,...

    Giuseppe Curcio, Daniela Tempesta, Simone Scarlata… in Neurological Sciences (2013)

  9. No Access

    Article

    Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines

    Over the last few years a lot of research has been done to develop novel metal-based anti-cancer drugs, with the aim of improving clinical effectiveness, reducing general toxicity, and broadening the spectrum ...

    Alessandro Zanella, Valentina Gandin, Marina Porchia… in Investigational New Drugs (2011)

  10. No Access

    Article

    Can an inert slee** pill affect sleep? Effects on polysomnographic, behavioral and subjective measures

    Since two recent meta-analyses on sleep changes associated with placebo in clinical trials suggested a beneficial effect of placebo treatments, pointing to a dissociation between subjective and objective measu...

    Fabiana Fratello, Giuseppe Curcio, Michele Ferrara, Cristina Marzano… in Psychopharmacology (2005)

  11. No Access

    Article

    Free Communication Abstracts

    Prashan T. Kaul, Jasonm Passafiume, Bruce F. O’Hara… in Sleep and Biological Rhythms (2005)