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within Article Remove this filter Christopher J. Bohlen Remove this filter Animal Genetics and Genomics Remove this filter

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    Article

    Integrative in situ map** of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease

    Complex diseases are characterized by spatiotemporal cellular and molecular changes that may be difficult to comprehensively capture. However, understanding the spatiotemporal dynamics underlying pathology can...

    Hu Zeng, Jiahao Huang, Haowen Zhou, William J. Meilandt… in Nature Neuroscience (2023)

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    Article

    Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

    Phagocytosis is required for a broad range of physiological functions, from pathogen defense to tissue homeostasis, but the mechanisms required for phagocytosis of diverse substrates remain incompletely unders...

    Michael S. Haney, Christopher J. Bohlen, David W. Morgens… in Nature Genetics (2018)