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  1. No Access

    Article

    A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

    The bite of the Texas coral snake, although not fatal, causes excruciating and long-lasting pain. The toxin involved has now been characterized. The purified active component (MitTx) results from an unusual co...

    Christopher J. Bohlen, Alexander T. Chesler, Reza Sharif-Naeini… in Nature (2011)

  2. No Access

    Article

    Neurotoxic reactive astrocytes are induced by activated microglia

    Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood. Here we show that a subtype of reactive astrocytes, which we termed A1, is indu...

    Shane A. Liddelow, Kevin A. Guttenplan, Laura E. Clarke, Frederick C. Bennett… in Nature (2017)