Skip to main content

and
  1. No Access

    Article

    OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data

    Julianus Pfeuffer, Chris Bielow, Samuel Wein, Kyowon Jeong, Eugen Netz in Nature Methods (2024)

  2. Article

    Open Access

    Integrative functional genomics decodes herpes simplex virus 1

    The predicted 80 open reading frames (ORFs) of herpes simplex virus 1 (HSV-1) have been intensively studied for decades. Here, we unravel the complete viral transcriptome and translatome during lytic infection...

    Adam W. Whisnant, Christopher S. Jürges, Thomas Hennig in Nature Communications (2020)

  3. Article

    Open Access

    Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer

    Metabolic alterations can serve as targets for diagnosis and cancer therapy. Due to the highly complex regulation of cellular metabolism, definite identification of metabolic pathway alterations remains challe...

    Nikolaus Berndt, Antje Egners, Guido Mastrobuoni in British Journal of Cancer (2020)

  4. No Access

    Article

    OpenMS: a flexible open-source software platform for mass spectrometry data analysis

    OpenMS is a flexible, user-friendly, open-source software platform for the biological analysis of mass spectrometry proteomics and metabolomics data. The modular platform allows developers to seamlessly genera...

    Hannes L Röst, Timo Sachsenberg, Stephan Aiche, Chris Bielow in Nature Methods (2016)

  5. Article

    Open Access

    Extensive identification and analysis of conserved small ORFs in animals

    There is increasing evidence that transcripts or transcript regions annotated as non-coding can harbor functional short open reading frames (sORFs). Loss-of-function experiments have identified essential devel...

    Sebastian D. Mackowiak, Henrik Zauber, Chris Bielow, Denise Thiel in Genome Biology (2015)