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Article
OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data
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Article
Open AccessIntegrative functional genomics decodes herpes simplex virus 1
The predicted 80 open reading frames (ORFs) of herpes simplex virus 1 (HSV-1) have been intensively studied for decades. Here, we unravel the complete viral transcriptome and translatome during lytic infection...
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Article
Open AccessKinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer
Metabolic alterations can serve as targets for diagnosis and cancer therapy. Due to the highly complex regulation of cellular metabolism, definite identification of metabolic pathway alterations remains challe...
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Article
OpenMS: a flexible open-source software platform for mass spectrometry data analysis
OpenMS is a flexible, user-friendly, open-source software platform for the biological analysis of mass spectrometry proteomics and metabolomics data. The modular platform allows developers to seamlessly genera...
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Article
Open AccessExtensive identification and analysis of conserved small ORFs in animals
There is increasing evidence that transcripts or transcript regions annotated as non-coding can harbor functional short open reading frames (sORFs). Loss-of-function experiments have identified essential devel...