Skip to main content

3 Result(s)

within Article Remove this filter Chris Abell Remove this filter Biomedicine, general Remove this filter

and

  1. No Access

    Article

    Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

  2. Protein–protein interactions (PPIs) are increasingly being targeted by drug discovery groups, and there exists great scope for therapeutic modulation of this t...

    3. Duncan E. Scott, Andrew R. Bayly, Chris Abell… in Nature Reviews Drug Discovery (2016)

  3. No Access

    Article

    High-throughput crystallography for lead discovery in drug design

  4. Knowledge of the three-dimensional structures of target proteins provides a starting point for structure-based approaches to drug design by defining the topogr...

    5. Tom L. Blundell, Harren Jhoti, Chris Abell in Nature Reviews Drug Discovery (2002)

  5. No Access

    Article

    Direct and sensitive detection of a human virus by rupture event scanning

    We have developed a sensitive, economical method that directly detects viruses by making use of the interaction between type 1 herpes simplex virus (HSV1) and specific antibodies covalently attached to the osc...

    Matthew A. Cooper, Fedor N. Dultsev, Tony Minson, Victor P. Ostanin… in Nature Biotechnology (2001)