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    Article

    Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

  2. Protein–protein interactions (PPIs) are increasingly being targeted by drug discovery groups, and there exists great scope for therapeutic modulation of this t...

    3. Duncan E. Scott, Andrew R. Bayly, Chris Abell… in Nature Reviews Drug Discovery (2016)

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    Article

    High-throughput crystallography for lead discovery in drug design

  4. Knowledge of the three-dimensional structures of target proteins provides a starting point for structure-based approaches to drug design by defining the topogr...

    5. Tom L. Blundell, Harren Jhoti, Chris Abell in Nature Reviews Drug Discovery (2002)