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  1. Article

    Open Access

    Global nucleosome occupancy in yeast

    Although eukaryotic genomes are generally thought to be entirely chromatin-associated, the activated PHO5 promoter in yeast is largely devoid of nucleosomes. We systematically evaluated nucleosome occupancy in ye...

    Bradley E Bernstein, Chih Long Liu, Emily L Humphrey, Ethan O Perlstein in Genome Biology (2004)

  2. Article

    Open Access

    RNA polymerase map** during stress responses reveals widespread nonproductive transcription in yeast

    The use of genome-wide RNA abundance profiling by microarrays and deep sequencing has spurred a revolution in our understanding of transcriptional control. However, changes in mRNA abundance reflect the combin...

    Tae Soo Kim, Chih Long Liu, Moran Yassour, John Holik, Nir Friedman in Genome Biology (2010)

  3. Article

    Open Access

    Data normalization considerations for digital tumor dissection

    In a recently published article in Genome Biology, Li and colleagues introduced TIMER, a gene expression deconvolution approach for studying tumor-infiltrating leukocytes (TILs) in 23 cancer types profiled by The...

    Aaron M. Newman, Andrew J. Gentles, Chih Long Liu, Maximilian Diehn in Genome Biology (2017)