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Open AccessThe CompactLight Design Study
CompactLight is a Design Study funded by the European Union under the Horizon 2020 research and innovation funding programme, with Grant Agreement No. 777431. CompactLight was conducted by an International Col...
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Risk factors and outcome of graft failure after HLA matched and mismatched unrelated donor hematopoietic stem cell transplantation: a study on behalf of SFGM-TC and SFHI
Graft failure remains a severe complication of hematopoietic stem cell transplantation (HSCT). Several risk factors have already been published. In this study, we re-evaluated them in a large cohort who had th...
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Nonlinear spectral cleaning of few-cycle pulses via cross-polarized wave (XPW) generation
The characterization of a temporal filter based on cross-polarized wave generation working in the few-optical-cycle regime is presented. We show that this device dramatically improves the spectral quality of t...
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Influence of spectral phase on cross-polarized wave generation with short femtosecond pulses
In this paper we present the first comprehensive study of the role of spectral phase on cross-polarized wave (XPW) generation using sub-30 femtosecond (fs) laser pulses. XPW generation improves the temporal co...
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Rare earth based clusters for nanoscale light source
We investigate the fundamental properties of films resulting from the deposition of Eu3+ doped Gd2O3 clusters. We first report that the crystalline structure of clusters with diameter as low as 2.8 nm is still BC...
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Venous blood lactate increase after vertical jum** in volleyball athletes
The aim of this study was to test the hypothesis that venous blood lactate concentrations ([La–]) would vary from the beginning of brief exercise. Maximal vertical jum** was used as a model of brief intense ex...
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DGGE screening of PKD1 gene reveals novel mutations in a large cohort of 146 unrelated patients
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most commonly inherited renal diseases. ADPKD is a genetically heterogeneous disorder involving at least three different genes. PKD1, the major ...
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Frequency measurements of hyperfine splittings in ground rovibronic states of I by stimulated resonant Raman spectroscopy
Measurements of hyperfine splittings in the ground electronic state of have been performed by stimulated Raman spectroscopy. An argon laser emitting at 514.5 nm, drives the c...
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Noninvasive skeletal muscle lactate detection between periods of intense exercise in humans
We investigated whether localized 1H nuclear magnetic resonance spectroscopy (NMRS) using stimulated echoes (STEAM) with a long mixing time (t m) allowed the suppression of the fat signal and detection of lactat...
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Metabolic and hormonal responses during repeated bouts of brief and intense exercise: effects of pre-exercise glucose ingestion
We investigated metabolic and hormonal responses during repeated bouts of brief and intense exercise (a force-velocity test; Fv test) and examined the effect of glucose ingestion on these responses and on exerci...
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Lactate kinetics during passive and partially active recovery in endurance and sprint athletes
We investigated the effects of passive and partially active recovery on lactate removal after exhausting cycle ergometer exercise in endurance and sprint athletes. A group of 14 men, 7 endurance-trained (ET) a...
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Lactate uptake by forearm skeletal muscles during repeated periods of short-term intense leg exercise in humans
We investigated the role of the forearm skeletal muscles in the removal of lactate during repeated periods of short-term intensive leg exercise, i.e. a force-velocity (FV) test known to induce a marked accumul...
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Internal carotid artery dissection following bronchos
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Neonatal screening for cystic fibrosis: result of a pilot study using both immunoreactive trypsinogen and cystic fibrosis gene mutation analyses
We have evaluated a two-tier neonatal cystic fibrosis (CF) screening of immunoreactive trypsinogen (IRT) followed by CFTR gene mutation analysis using a systematic scanning of exons 7, 10, and 11, and, if nece...
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Aerobic and anaerobic contribution to Wingate test performance in sprint and middle-distance runners
We investigated the aerobic and anaerobic contributions to performance during the Wingate test in sprint and middle-distance runners and whether they were related to the peak aerobic and anaerobic performances...
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Complete detection of mutations in cystic fibrosis patients of Native American origin
An increased incidence of cystic fibrosis (CF) has been reported in some populations of Native Americans of the Southwest such as the Pueblo, which is a genetic isolate. As the most common mutation found in Ca...
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Effects of 2-chloropropionate on venous plasma lactate concentration and anaerobic power during periods of incremental intensive exercise in humans
We investigated the effects of a stimulation of pyruvate dehydrogenase (PDH) activity induced by 2-chloropropionate (2-CP) on venous plasma lactate concentration and peak anaerobic power (W an, peak) during perio...
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Retrospective study of the cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in Guthrie cards from a large cohort of neonatal screening for cystic fibrosis
The cystic fibrosis transmembrane conductance regulator (CFTR) gene encodes a cAMP-activated chloride channel, and in individuals with both alleles of the gene mutated, symptoms of CF disease are manifest. Wit...
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Anaerobic and aerobic components during arm-crank exercise in sprint and middle-distance swimmers
The purpose of this investigation was to compare anaerobic and aerobic components measured during arm exercise in sprint and middle-distance swimmers and to investigate whether the peak anaerobic power :peak a...
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A novel mutation in exon 3 of the CFTR gene
We have screened the 27 exons of the cystic fibrosis transmembrane conductance regulator gene in 87 non-ΔF508 chromosomes of Breton origin using the combined techniques of denaturing gradient gel electrophores...