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  1. No Access

    Article

    Vascular safety during arthroscopic all-inside meniscus suture

    The purpose of the study is to assess the orientation and distance of the popliteal artery (PA) from both the anteromedial and anterolateral portals.

    Akinobu Nishimura, Aki Fukuda, Ko Kato in Knee Surgery, Sports Traumatology, Arthros… (2015)

  2. No Access

    Article

    Elevated soluble platelet glycoprotein VI is a useful marker for DVT in postoperative patients treated with edoxaban

    Prevention of deep vein thrombosis (DVT) is important in patients undergoing major orthopedic surgery. Although the detection of an elevated d-dimer level is useful for predicting DVT, it is not efficacious in p...

    Takumi Aota, Katsuki Naitoh, Hideo Wada in International Journal of Hematology (2014)

  3. No Access

    Article

    Clinical outcomes of Kyocera Modular Limb Salvage system after resection of bone sarcoma of the distal part of the femur: the Japanese Musculoskeletal Oncology Group study

    The Japanese Musculoskeletal Oncology Group have developed an original prosthesis called the Kyocera Modular Limb Salvage system (KMLS system). This prosthesis has a semi-rotating hinge joint and is particular...

    Tomoki Nakamura, Akihiko Matsumine, Atsumasa Uchida in International Orthopaedics (2014)

  4. No Access

    Article

    Prevalence of hallux valgus and risk factors among Japanese community dwellers

    To investigate the prevalence and severity of radiographically detected hallux valgus (HV) as well as associated risk factors among Japanese residents of Miyagawa, a mountain village located in the center of M...

    Akinobu Nishimura, Ko Kato, Aki Fukuda, Shigeto Nakazora in Journal of Orthopaedic Science (2014)

  5. No Access

    Article

    The efficacy of rebamipide add-on therapy in arthritic patients with COX-2 selective inhibitor-related gastrointestinal events: a prospective, randomized, open-label blinded-endpoint pilot study by the GLORIA study group

    We aimed to confirm the effect of combined treatment with celecoxib and rebamipide would be more effective than celecoxib alone for prevention of upper gastrointestinal (GI) events.

    Masahiro Hasegawa, Noriyuki Horiki, Kyosuke Tanaka in Modern Rheumatology (2013)

  6. No Access

    Article

    The thrombin inhibitor, argatroban, inhibits breast cancer metastasis to bone

    Breast cancer has the potential to metastasize to bone, causing debilitating symptoms. Although many tumor cells have thrombin-generating systems originating from tissue factor (TF), therapy in terms of the co...

    Kunihiro Asanuma, Hiroki Wakabayashi, Takayuki Okamoto, Yumiko Asanuma in Breast Cancer (2013)

  7. Article

    Open Access

    Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors

    Neural-cadherin (N-cadherin) is one of the most important molecules involved in tissue morphogenesis, wound healing, and the maintenance of tissue integrity. Recently, the cleavage of N-cadherin has become a f...

    Rui Niimi, Akihiko Matsumine, Takahiro Iino, Shigeto Nakazora in BMC Cancer (2013)

  8. Article

    Open Access

    Protective effect of edaravone for tourniquet-induced ischemia-reperfusion injury on skeletal muscle in murine hindlimb

    Studies have shown that ischemia-reperfusion (I/R) produces free radicals leading to lipid peroxidation and damage to skeletal muscle. The purposes of this study were 1) to assess the histological findings of ...

    Kazuichiro Hori, Masaya Tsujii, Takahiro Iino in BMC Musculoskeletal Disorders (2013)

  9. Article

    Open Access

    Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study

    Platelet-rich plasma (PRP) is a fraction of plasma in which several growth factors are concentrated at high levels. The active soluble releasate isolated following platelet activation of PRP (PRP-releasate) ha...

    Shuji Obata, Koji Akeda, Takao Imanishi, Koichi Masuda in Arthritis Research & Therapy (2012)

  10. No Access

    Article

    Prevalence and characteristics of unilateral knee osteoarthritis in a community sample of elderly Japanese: do fractures around the knee affect the pathogenesis of unilateral knee osteoarthritis?

    The purpose of this study was to investigate the prevalence and characteristics of unilateral knee osteoarthritis (KOA), to investigate what percent of contralateral healthy knees in patients with unilateral K...

    Akinobu Nishimura, Masahiro Hasegawa, Hiroki Wakabayashi in Journal of Orthopaedic Science (2012)

  11. No Access

    Article

    Increased fibrinolysis increases bleeding in orthopedic patients receiving prophylactic fondaparinux

    We evaluated hemostatic markers in patients who underwent major orthopedic surgery, including total hip and total knee arthroplasty, and were treated for the prophylaxis of deep vein thrombosis (DVT) with or w...

    Kakunoshin Yoshida, Hideo Wada, Masahiro Hasegawa in International Journal of Hematology (2012)

  12. Article

    Open Access

    The adverse effect of an unplanned surgical excision of foot soft tissue sarcoma

    Malignant soft tissue tumors of the foot are extremely rare and thus can be prematurely excised without appropriate preoperative evaluation. The present study compares adverse effects between unplanned and pla...

    Akinobu Nishimura, Akihiko Matsumine in World Journal of Surgical Oncology (2011)

  13. No Access

    Article

    Monitoring for anti-Xa activity for prophylactic administration of Fondaparinux in patients with artificial joint replacement

    The efficacy of measuring anti-Xa activity was evaluated in major orthopedic surgery patients receiving thrombo-prophylaxis with Fondaparinux. Although 98 orthopedic patients including those receiving total hi...

    Kakunoshin Yoshida, Hideo Wada, Masahiro Hasegawa in International Journal of Hematology (2011)

  14. No Access

    Article

    Risk factors for the incidence and progression of radiographic osteoarthritis of the knee among Japanese

    This longitudinal study aimed to identify risk factors for the incidence and progression of radiographic knee osteoarthritis (OA). We examined the inhabitants of Miyagawa village aged ≥65 years every two years...

    Akinobu Nishimura, Masahiro Hasegawa, Ko Kato, Tomomi Yamada in International Orthopaedics (2011)

  15. No Access

    Article

    A novel hyperthermia treatment for bone metastases using magnetic materials

    Patients with bone metastases in the extremities sometimes require surgical intervention to prevent deterioration of quality of life due to a pathological fracture. The use of localized radiotherapy combined w...

    Akihiko Matsumine, Kenji Takegami in International Journal of Clinical Oncology (2011)

  16. No Access

    Article

    Distribution and role of tenascin-C in human osteoarthritic cartilage

    Tenascin-C (TN-C) is expressed in the cartilage of osteoarthritis (OA). We examined whether TN-C was involved in cartilage repair of the diseased joints. Human articular cartilage samples were obtained from pa...

    Yutaka Nakoshi, Masahiro Hasegawa, Koji Akeda in Journal of Orthopaedic Science (2010)

  17. No Access

    Article

    Retrospective clinical study of the efficacy of lower-dose methotrexate and infliximab therapy in patients with rheumatoid arthritis

    The objective of this study is to compare the long-term outcomes of infliximab therapy with lower-dose methotrexate (MTX; ≤4 mg per week) and with standard-dose MTX (≥6 mg per week) in Japanese rheumatoid arth...

    Hiroki Wakabayashi, Akihiro Sudo, Masahiro Hasegawa, Hiroshi Oka in Clinical Rheumatology (2010)

  18. No Access

    Article

    Epithelioid hemangioendothelioma after radiotherapy for congenital hemangioma: a case report

    A rare case of post-radiation epithelioid hemangioendothelioma arising in a congenital hemangioma of the lower leg 18 years after radiotherapy is reported. At 7 years of age, the patient underwent partial rese...

    Rui Niimi, Akihiko Matsumine, Katsuyuki Kusuzaki, Ken Shintani in Medical Oncology (2010)

  19. No Access

    Article

    Ganglion cyst arising from the posterolateral capsule of the knee

    Aki Fukuda, Ko Kato, Akihiro Sudo, Atsumasa Uchida in Journal of Orthopaedic Science (2010)

  20. No Access

    Article

    Clinical application of a handy intraoperative measurement device for lumbar segmental instability

    We describe the development of a new device that permits handy intraoperative measurement of lumbar segmental instability. The subjects comprised 80 patients with lumbar degenerative disease. Relationships bet...

    Yuichi Kasai, Tadashi Inaba, Takaya Kato, Koji Akeda in International Orthopaedics (2010)

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