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within Article Remove this filter Anna Kreutzman Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    Evolution and modulation of antigen-specific T cell responses in melanoma patients

    Analyzing antigen-specific T cell responses at scale has been challenging. Here, we analyze three types of T cell receptor (TCR) repertoire data (antigen-specific TCRs, TCR-repertoire, and single-cell RNA + TC...

    Jani Huuhtanen, Liang Chen, Emmi Jokinen, Henna Kasanen… in Nature Communications (2022)

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  2. Article

    Open Access

    The tumor and plasma cytokine profiles of renal cell carcinoma patients

    Renal cell carcinoma (RCC) accounts for 90% of all renal cancers and is considered highly immunogenic. Although many studies have reported the circulating peripheral cytokine profiles, the signatures between t...

    Moon Hee Lee, Essi Laajala, Anna Kreutzman, Petrus Järvinen… in Scientific Reports (2022)

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  3. Article

    Open Access

    Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease

    Graft versus host disease (GvHD) is the main complication of allogeneic hematopoietic stem cell transplantation (HSCT). Here we report studies of a patient with chronic GvHD (cGvHD) carrying persistent CD4+ T cel...

    Daehong Kim, Giljun Park, Jani Huuhtanen, Sofie Lundgren… in Nature Communications (2020)

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